Ethyl alpha-Iodophenylacetate

Base Information

Chemical Name:Ethyl alpha-Iodophenylacetate
CAS No.:78489-65-3
Molecular Formula:C₁₀H₁₁IO₂
Molecular Weight:290.101
Hs Code.:
European Community (EC) Number:834-033-4
Nikkaji Number:J3.442.874C

Synonyms:Ethyl alpha-Iodophenylacetate;ethyl 2-iodo-2-phenylacetate;78489-65-3;alpha-Iodophenylacetic Acid Ethyl Ester;Ethylalpha-Iodophenylacetate;SCHEMBL8872032;GFYUBPKXVMWINH-UHFFFAOYSA-;MFCD29905039;2-Iodo-2-phenylacetic Acid Ethyl Ester;CS-0435502;E1200;D90601;InChI=1/C10H11IO2/c1-2-13-10(12)9(11)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3

Suppliers and Price of Ethyl alpha-Iodophenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl α-Iodophenylacetate
500mg
$ 75.00

TRC
Ethyl α-Iodophenylacetate
100mg
$ 60.00

TRC
Ethyl α-Iodophenylacetate
50mg
$ 45.00

TCI Chemical
Ethyl α-Iodophenylacetate >98.0%(HPLC)
25g
$ 253.00

TCI Chemical
Ethyl α-Iodophenylacetate >98.0%(HPLC)
5g
$ 85.00

AK Scientific
Ethylalpha-Iodophenylacetate
25g
$ 405.00

Total 6 raw suppliers

Chemical Property of Ethyl alpha-Iodophenylacetate

Chemical Property:

Refractive Index:1.5780 to 1.5820
Boiling Point:302.2±30.0 °C(Predicted)
Density:1.626±0.06 g/cm3(Predicted)
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:289.98038
Heavy Atom Count:13
Complexity:164

Purity/Quality:

97% ^*data from raw suppliers

Ethyl α-Iodophenylacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=CC=C1)I

Technology Process of Ethyl alpha-Iodophenylacetate

There total 3 articles about Ethyl alpha-Iodophenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 2882-19-1,2216-90-2
ethyl 2-phenyl-2-bromoacetate

: 78489-65-3
ethyl α-iodophenylacetate

Guidance literature:: With sodium iodide; In acetone; at 25 ℃; for 2h;
DOI:10.1021/ma501569j

Reference yield: 53.0%

: 101-97-3
Ethyl 2-phenylethanoate

: 13638-89-6
meso-diethyl 2,3-diphenylsuccinate

: 78489-65-3
ethyl α-iodophenylacetate

Guidance literature:: With iodine; lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; Product distribution; differently prepared lithium reagents;

Reference yield:

: 101-97-3
Ethyl 2-phenylethanoate

: 78489-65-3
ethyl α-iodophenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

2: sodium iodide / acetone / 20 °C

With N-Bromosuccinimide; sodium iodide; dibenzoyl peroxide; In tetrachloromethane; acetone;
DOI:10.1021/acs.orglett.6b02353