1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole

Base Information

Chemical Name:1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole
CAS No.:80985-57-5
Molecular Formula:C₁₈H₂₁N₅O₂
Molecular Weight:339.397
Hs Code.:
NSC Number:364579,360519
DSSTox Substance ID:DTXSID30420191

Synonyms:NSC364579;80985-57-5;DTXSID30420191;NSC360519;NSC-360519;NSC-364579;1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole;4-(1-morpholino-5H-pyridazino[4,5-b]indol-4-yl)morpholine

Suppliers and Price of 1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole

Chemical Property:

Vapor Pressure:1.58E-18mmHg at 25°C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:339.16952493
Heavy Atom Count:25
Complexity:455

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=NN=C(C3=C2C4=CC=CC=C4N3)N5CCOCC5

Technology Process of 1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole

There total 3 articles about 1,4-Di(4-morpholinyl)-5H-pyridazino[4,5-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 110-91-8,99108-56-2
morpholine

: 80985-56-4
1,4-dichloro-5H-pyridazino<4,5-b>indole

: 80985-57-5
1,4-bis(N-morpholino)-5H-pyridazino<4,5-b>indole

Guidance literature:: for 4h; Heating;
DOI:10.1002/jhet.5570180808

Reference yield:

: 54781-93-0
1H-indole-2,3-dicarboxylic acid dimethyl ester

: 80985-57-5
1,4-bis(N-morpholino)-5H-pyridazino<4,5-b>indole

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / 98percent N₂H₄*H₂O / ethanol / 10 h / Heating

2: 90 percent / POCl₃ / 4 h / 90 °C

3: 82 percent / 4 h / Heating

With hydrazine hydrate; trichlorophosphate; In ethanol;
DOI:10.1002/jhet.5570180808

Reference yield:

: 80985-55-3
1,4-dioxo-1,2,3,4-tetrahydro-5H-pyridazino<4,5-b>indole

: 80985-57-5
1,4-bis(N-morpholino)-5H-pyridazino<4,5-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / POCl₃ / 4 h / 90 °C

2: 82 percent / 4 h / Heating

With trichlorophosphate;
DOI:10.1002/jhet.5570180808