N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

Base Information

Chemical Name:N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine
CAS No.:1266729-02-5
Molecular Formula:C₁₄H₁₄FN
Molecular Weight:215.27
Hs Code.:

Synonyms:

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Chemical Property of N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

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Technology Process of N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

There total 4 articles about N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₄H₁₂FN

: 1266729-02-5
N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

Guidance literature:: C₁₄H₁₂FN; With methanol; sodium tetrahydroborate; In dichloromethane; at 20 ℃; for 1h;

With water; sodium hydrogencarbonate; In dichloromethane;

Reference yield:

: 79996-88-6
(4-fluoronaphthalen-1-yl)methanol

: 1266729-02-5
N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

Guidance literature:: Multi-step reaction with 3 steps

1: Dess-Martin periodane / dichloromethane / 1 h / 0 °C

2: magnesium sulfate / dichloromethane / 18 h / 20 °C

3: sodium tetrahydroborate; methanol / dichloromethane / 1 h / 20 °C

With methanol; sodium tetrahydroborate; magnesium sulfate; Dess-Martin periodane; In dichloromethane;

Reference yield:

: 172033-73-7
4-fluoro-1-naphthalenecarbaldehyde

: 1266729-02-5
N-((4-fluoronaphthalen-1-yl)methyl)cyclopropanamine

Guidance literature:: Multi-step reaction with 2 steps

1: magnesium sulfate / dichloromethane / 18 h / 20 °C

2: sodium tetrahydroborate; methanol / dichloromethane / 1 h / 20 °C

With methanol; sodium tetrahydroborate; magnesium sulfate; In dichloromethane;