1-Cycloheptyl-4-piperidinaMine 2HCl

Base Information

• Chemical Name: 1-Cycloheptyl-4-piperidinaMine 2HCl
• CAS No.: 886508-40-3
• Molecular Formula: C₁₂H₂₄N₂
• Molecular Weight: 196.336
• Hs Code.: 2933399990
• Mol file: 886508-40-3.mol

Synonyms:

Chemical Property of 1-Cycloheptyl-4-piperidinaMine 2HCl

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1-Cycloheptyl-4-piperidinaminedihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Cycloheptyl-4-piperidinaMine 2HCl

There total 3 articles about 1-Cycloheptyl-4-piperidinaMine 2HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-1-benzylpiperidine (50541-93-0) → 1-cycloheptyl-piperidin-4-ylamine (886508-40-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / Et₃N / CH₂Cl₂ / 12 h / 20 °C

2: H₂ / 20percent Pd(OH)2/C / methanol / 12 h / 20 °C / 2585.81 Torr

3: aq. NH₃ / methanol / 4 h / Heating

With ammonium hydroxide; hydrogen; triethylamine; 20percent Pd(OH)2/C; In methanol; dichloromethane;

DOI:10.1021/jm0100077

Reference yield:

N-(1-benzyl-4-piperidinyl)-2,2,2-trifluoroacetamide (97181-50-5) → 1-cycloheptyl-piperidin-4-ylamine (886508-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 20percent Pd(OH)2/C / methanol / 12 h / 20 °C / 2585.81 Torr

2: aq. NH₃ / methanol / 4 h / Heating

With ammonium hydroxide; hydrogen; 20percent Pd(OH)2/C; In methanol;

DOI:10.1021/jm0100077

Reference yield:

N-(1-cycloheptyl-piperidin-4-yl)-2,2,2-trifluoro-acetamide (1026386-30-0) → 1-cycloheptyl-piperidin-4-ylamine (886508-40-3)

Guidance literature:

With ammonium hydroxide; In methanol; for 4h; Heating;

DOI:10.1021/jm0100077

upstream raw materials:

N-(1-cycloheptyl-piperidin-4-yl)-2,2,2-trifluoro-acetamide

4-amino-1-benzylpiperidine

N-(1-benzyl-4-piperidinyl)-2,2,2-trifluoroacetamide