cyano(3-phenoxyphenyl)methyl octahydro-3aH-4,7-methanoindene-3a-carboxylate

Base Information

• Chemical Name: cyano(3-phenoxyphenyl)methyl octahydro-3aH-4,7-methanoindene-3a-carboxylate
• CAS No.: 93107-41-6
• Molecular Formula: C₂₅H₂₅NO₃
• Molecular Weight: 387.478
• Mol file: 93107-41-6.mol

Synonyms:

Chemical Property of cyano(3-phenoxyphenyl)methyl octahydro-3aH-4,7-methanoindene-3a-carboxylate

Chemical Property:

• Vapor Pressure: 5.43E-11mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyano(3-phenoxyphenyl)methyl octahydro-3aH-4,7-methanoindene-3a-carboxylate

There total 4 articles about cyano(3-phenoxyphenyl)methyl octahydro-3aH-4,7-methanoindene-3a-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-hydroxy-2-(3-phenoxyphenyl)acetonitrile (39515-47-4) + (3aR,4S,7R,7aR)-Octahydro-4,7-methano-indene-3a-carbonyl chloride → α-cyano-m-phenoxybenzyl endo-tricyclo<5.2.1.02,6>decane-exo-2-carboxylate (93107-41-6)

Guidance literature:

With pyridine; In benzene; for 12h; Heating;

Reference yield: 35.0%

2-hydroxy-2-(3-phenoxyphenyl)acetonitrile (39515-47-4) + exo-Tricyclo<5.2.1.02,6>decan-endo-carbonsaeure-(2)-chlorid (80623-06-9,80657-63-2,119718-96-6) → α-cyano-m-phenoxybenzyl exo-tricyclo<5.2.1.02,6>decane-endo-2-carboxylate (93107-41-6)

Guidance literature:

With pyridine; In benzene; for 15h; Heating;

Reference yield:

2-carboxy-exo-tetrahydrodicyclopentadiene (80394-98-5,80433-66-5,148810-36-0) → α-cyano-m-phenoxybenzyl exo-tricyclo<5.2.1.02,6>decane-endo-2-carboxylate (93107-41-6)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / benzene / 7 h / Heating

2: 35 percent / pyridine / benzene / 15 h / Heating

With pyridine; thionyl chloride; In benzene;

upstream raw materials:

2-hydroxy-2-(3-phenoxyphenyl)acetonitrile

exo-Tricyclo<5.2.1.0^2,6>decan-endo-carbonsaeure-(2)-chlorid

2-carboxy-exo-tetrahydrodicyclopentadiene