Ethyl 2-(3-(bromomethyl)phenyl)acetate

Base Information

Chemical Name:Ethyl 2-(3-(bromomethyl)phenyl)acetate
CAS No.:140215-42-5
Molecular Formula:C11H13BrO2
Molecular Weight:257.127
Hs Code.:
DSSTox Substance ID:DTXSID30441821
Wikidata:Q82258781

Synonyms:140215-42-5;ethyl 2-(3-(bromomethyl)phenyl)acetate;Ethyl 2-[3-(bromomethyl)phenyl]acetate;ethyl (3-bromomethylphenyl)acetate;MFCD12912065;ethyl(3-(bromomethyl)phenyl)acetate;ethyl[3-(bromomethyl)phenyl]acetate;Benzeneacetic acid, 3-(bromomethyl)-, ethyl ester;ethyl 3-(bromomethyl)phenylacetate;(3-bromomethyl-phenyl)-acetic acid ethyl ester;SCHEMBL1125421;ethyl(3-bromomethylphenyl)acetate;DTXSID30441821;VZARWHJHIUIKHF-UHFFFAOYSA-N;ethyl [3-(bromomethyl)phenyl]acetate;ethyl2-(3-(bromomethyl)phenyl)acetate;HR-0009;ethyl 2-[3-(bromomethyl)phenyl]-acetate;SY270298;3-(Bromomethyl)benzeneacetic acid ethyl ester;3-[Bromomethyl]benzeneacetic acid, ethyl ester;P16763;A904882

Suppliers and Price of Ethyl 2-(3-(bromomethyl)phenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Ethyl 2-(3-(bromomethyl)phenyl)acetate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:256.00989
Heavy Atom Count:14
Complexity:182

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CC(=CC=C1)CBr

Technology Process of Ethyl 2-(3-(bromomethyl)phenyl)acetate

There total 8 articles about Ethyl 2-(3-(bromomethyl)phenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 40061-55-0
ethyl m-methylphenylacetate

: 140215-42-5
(3-bromomethylphenyl)acetic acid ethyl ester

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 16h; Reflux;

Reference yield:

: 272130-46-8
ethyl (3-hydroxymethylphenyl)acetate

: 140215-42-5
(3-bromomethylphenyl)acetic acid ethyl ester

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1021/jm990448e

Reference yield:

: 1878-67-7
3-Bromophenylacetic acid

: 140215-42-5
(3-bromomethylphenyl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: 98 percent / H₂SO₄ / 96 h / Heating

2.1: Pd(PPh₃)4 / dimethylformamide / 36 h / 80 °C

3.1: N-methylmorpholine N-oxide; OsO₄ / 2-methyl-propan-2-ol; tetrahydrofuran; H₂O / 7 h / 20 °C

3.2: NaHCO₃; NaIO₄ / 2-methyl-propan-2-ol; tetrahydrofuran; H₂O / 0.75 h

4.1: NaBH₄ / methanol / 1 h / 20 °C

5.1: PPh₃; CBr₄ / CH₂Cl₂ / 0.5 h / 0 °C

With sodium tetrahydroborate; osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; carbon tetrabromide; sulfuric acid; 4-methylmorpholine N-oxide; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1.1: Esterification / 2.1: Alkylation / 3.1: Oxidation / 3.2: Oxidative cleavage / 4.1: Reduction / 5.1: Bromination;
DOI:10.1021/jm990448e