Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate
CAS No.:908350-29-8
Molecular Formula:C₁₃H₁₄N₂O₃
Molecular Weight:246.266
Hs Code.:2933499090
European Community (EC) Number:804-488-3
DSSTox Substance ID:DTXSID60586471
Wikidata:Q82478617
Mol file:908350-29-8.mol

Synonyms:Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate;908350-29-8;4-amino-6-methoxyquinoline-3-carboxylic acid ethyl ester;SCHEMBL438203;DTXSID60586471;KWSSHDCTTIZJJQ-UHFFFAOYSA-N;BBL012824;MFCD09761113;STK787823;AKOS000272084;MCULE-7676409077;VS-03537;DB-108867;CS-0312808;VU0612450-1;ethyl-4-amino-6-methoxyquinoline-3-carboxylate;F3367-0010;4-Amino-6-methoxyquinoline-3-carboxylic acid ethyl ester, AldrichCPR

Suppliers and Price of Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Amino-6-methoxyquinoline-3-carboxylic acid ethyl ester
1 g
$ 384.00

Sigma-Aldrich
4-Amino-6-methoxyquinoline-3-carboxylic acid ethyl ester Aldrich
1g
$ 258.00

AK Scientific
Ethyl4-Amino-6-methoxyquinoline-3-carboxylate
1g
$ 386.00

Total 3 raw suppliers

Chemical Property of Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:246.10044231
Heavy Atom Count:18
Complexity:298

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-6-methoxyquinoline-3-carboxylic acid ethyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C2C=CC(=CC2=C1N)OC

Technology Process of Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate

There total 4 articles about Ethyl 4-Amino-6-methoxyquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 22931-71-1
ethyl 4-chloro-6-methoxyquinolin-3-carboxylate

: 908350-29-8
ethyl 4-amino-6-methoxyquinoline-3-carboxylate

Guidance literature:: With ammonia; In isopropyl alcohol;

Reference yield:

: 77156-78-6
ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate

: 908350-29-8
ethyl 4-amino-6-methoxyquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate

2: ammonia / isopropyl alcohol

With ammonia; In isopropyl alcohol; trichlorophosphate;

Reference yield:

: 104-94-9
4-methoxy-aniline

: 908350-29-8
ethyl 4-amino-6-methoxyquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4 h / 120 °C / Inert atmosphere

1.2: 8 h / 260 °C / Inert atmosphere

2.1: trichlorophosphate / 3 h / Reflux; Inert atmosphere

3.1: ammonia / water; isopropyl alcohol / 110 °C

With ammonia; trichlorophosphate; In water; isopropyl alcohol;