Dotarem

Base Information

Chemical Name:Dotarem
CAS No.:92943-93-6
Molecular Formula:C₇H₁₇NO₅*C₁₆H₂₄GdN₄O₈*H
Molecular Weight:753.862
Hs Code.:
UNII:L0ND3981AG
Wikidata:Q27144071

Synonyms:Dotarem;gadoterate meglumine

Suppliers and Price of Dotarem

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 31 raw suppliers

Chemical Property of Dotarem

Chemical Property:

Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:11
Exact Mass:754.20202
Heavy Atom Count:42
Complexity:644

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC(C(C(C(CO)O)O)O)O.C1CN(CCN(CCN(CCN1CC(=O)O)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
Isomeric SMILES:CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.C1CN(CCN(CCN(CCN1CC(=O)O)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
Recent ClinicalTrials:Collagen-targeted PET Imaging for Early Interstitial Lung Disease
Recent EU Clinical Trials:Performance of Elucirem? (gadopiclenol) in Dynamic Susceptibility Contrast Magnetic Resonance Imaging (DSC-MRI) perfusion of brain gliomas
Uses Gadolinium Dota Meglumine is used in the preparation of Macrocyclic Gadolinium-?Based Contrast Agents.

Technology Process of Dotarem

There total 1 articles about Dotarem which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: gadolinium(III) oxide

: 60239-18-1
1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane

: 6284-40-8,97780-33-1
1-deoxy-1-(methylamino)-D-glucitol

: 92943-93-6
gadoterate meglumine

Guidance literature:: gadolinium(III) oxide; 1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane; In water; at 85 ℃;

1-deoxy-1-(methylamino)-D-glucitol; In water; pH=4;