Technology Process of (22R,23R,24S)-22,23-isopropylidenedioxy-3β-methanesulfonyloxy-5α-ergostane
There total 10 articles about (22R,23R,24S)-22,23-isopropylidenedioxy-3β-methanesulfonyloxy-5α-ergostane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 61 percent / tetrahydrofuran / 1 h / Ambient temperature
2: 95 percent / propionic acid / xylene / 2 h / Heating
3: LiAlH4 / tetrahydrofuran / 2 h / Heating
4: Et3N / toluene / 2 h / Ambient temperature
5: LiAlH4 / tetrahydrofuran / 2 h / Heating
6: 50 percent / potassium hexacyanoferrate(III), K2CO3, methanesulfonamide, dihydroquinidine p-chlorobenzoate, OsO4 / H2O; 2-methyl-propan-2-ol / 360 h / Ambient temperature
7: 99 percent / p-toluenesulfonic acid, H2O / dioxane / 4 h / Heating
8: 99 percent / H2 / 10percent Pd/C / ethanol / 2 h / 45 °C
9: p-toluenesulfonic acid / 1 h / Ambient temperature
10: pyridine / 1 h / Ambient temperature
With
pyridine; osmium(VIII) oxide; lithium aluminium tetrahydride; dihydroquinidine 4-chlorobenzoate; methanesulfonamide; water; hydrogen; potassium carbonate; toluene-4-sulfonic acid; propionic acid; triethylamine; potassium hexacyanoferrate(III);
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water; toluene; xylene; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 99 percent / H2 / 10percent Pd/C / ethanol / 2 h / 45 °C
2: p-toluenesulfonic acid / 1 h / Ambient temperature
3: pyridine / 1 h / Ambient temperature
With
pyridine; hydrogen; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
ethanol;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Et3N / toluene / 2 h / Ambient temperature
2: LiAlH4 / tetrahydrofuran / 2 h / Heating
3: 50 percent / potassium hexacyanoferrate(III), K2CO3, methanesulfonamide, dihydroquinidine p-chlorobenzoate, OsO4 / H2O; 2-methyl-propan-2-ol / 360 h / Ambient temperature
4: 99 percent / p-toluenesulfonic acid, H2O / dioxane / 4 h / Heating
5: 99 percent / H2 / 10percent Pd/C / ethanol / 2 h / 45 °C
6: p-toluenesulfonic acid / 1 h / Ambient temperature
7: pyridine / 1 h / Ambient temperature
With
pyridine; osmium(VIII) oxide; lithium aluminium tetrahydride; dihydroquinidine 4-chlorobenzoate; methanesulfonamide; water; hydrogen; potassium carbonate; toluene-4-sulfonic acid; triethylamine; potassium hexacyanoferrate(III);
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water; toluene; tert-butyl alcohol;
