25819-77-6Relevant articles and documents
Synthesis of 23,23-difluoro-25-hydroxyvitamin D3
Taguchi,Mitsuhashi,Yamanouchi,et al.
, p. 4933 - 4936 (1984)
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Stereocontrolled synthesis of dafachronic acid A, the ligand for the DAF-12 nuclear receptor of Caenorhabditis elegans
Giroux, Simon,Corey
, p. 9866 - 9867 (2007)
An efficient synthetic route to the DAF-12 nuclear receptor ligand of C. elegans, dafachronic acid, is described that starts with the abundant plant sterol β-stigmasterol and proceeds in 37% overall yield. The synthesis establishes the structure of this r
Probing the mechanism of action of amphotericin B
James, Phillip R.,Rawlings, Bernard J.
, p. 505 - 508 (1996)
Transmembrane spanning dimers of cholesterol were unable to form ion channels with amphotericin B: We suggest that the two 'half pores' as proposed by De Kruijff may be aligned unsymmetrically.
Formal Semisynthesis of Demethylgorgosterol Utilizing a Stereoselective Intermolecular Cyclopropanation Reaction
Rosenbaum, Nicolai,Schmidt, Lisa,Mohr, Florian,Fuhr, Olaf,Nieger, Martin,Br?se, Stefan
supporting information, p. 1568 - 1574 (2021/02/26)
In this study, we report a convenient and high yielding formal semisynthesis of demethylgorgosterol, a marine steroid with an intriguing sidechain containing a cyclopropane unit. This was achieved through the synthesis of an advanced ketone intermediate.
Synthesis of [26,27-2H6]brassinosteroids from 23,24-bisnorcholenic acid methyl ester
Antonchick, Andrey P.,Schneider, Bernd,Zhabinskii, Vladimir N.,Khripach, Vladimir A.
, p. 617 - 628 (2007/10/03)
A number of hexadeuterated brassinosteroids (BS) containing a hydroxy group at C-22 or a 22R,23R-diol function were prepared starting from 23,24-bisnorcholenic acid methyl ester for biosynthetic studies. Synthesis of the cyclic part was accomplished via t