3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine

Base Information

• Chemical Name: 3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine
• CAS No.: 116855-06-2
• Molecular Formula: C₇H₆ClN₃
• Molecular Weight: 167.598
• DSSTox Substance ID: DTXSID80556419
• Wikidata: Q82437963

Synonyms:3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine;116855-06-2;3-CHLORO-1-METHYLPYRAZOLO[3,4-B]PYRIDINE;DTXSID80556419;CS-0339144

Chemical Property of 3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 167.0250249
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C2=C(C=CC=N2)C(=N1)Cl

Technology Process of 3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine

There total 3 articles about 3-chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

3-amino-1-methylpyrazolo<3,4-b>pyridine (72583-83-6) → 3-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine (116855-06-2)

Guidance literature:

With tetrachloromethane; n-Butyl nitrite; for 3h; Heating;

DOI:10.1139/v88-074

Reference yield:

3-cyanopyridine N-oxide (14906-64-0) → 3-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine (116855-06-2)

Guidance literature:

Multi-step reaction with 3 steps

1: POCl₂ / 6 h / Heating

2: 46 percent / ethanol / 10 h / Heating

3: 58 percent / carbon tetrachloride, butyl nitrite / 3 h / Heating

With tetrachloromethane; n-Butyl nitrite; In ethanol;

DOI:10.1139/v88-074

Reference yield:

2-chloro-3-pyridinecarbonitrile (6602-54-6) → 3-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine (116855-06-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / ethanol / 10 h / Heating

2: 58 percent / carbon tetrachloride, butyl nitrite / 3 h / Heating

With tetrachloromethane; n-Butyl nitrite; In ethanol;

DOI:10.1139/v88-074

upstream raw materials:

3-amino-1-methylpyrazolo<3,4-b>pyridine

3-cyanopyridine N-oxide

2-chloro-3-pyridinecarbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 116855-06-2 3-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send