chevalone C

Base Information

• Chemical Name: chevalone C
• CAS No.: 1318025-77-2
• Molecular Formula: C₂₈H₄₀O₅
• Molecular Weight: 456.623
• Mol file: 1318025-77-2.mol

Synonyms:

Chemical Property of chevalone C

Chemical Property:

Purity/Quality:

≥95% ^*data from raw suppliers

Chevalone C ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells.

Technology Process of chevalone C

There total 1 articles about chevalone C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.7%

aszonapyrone B → chevalone E + chevalone C (1318025-77-2) + chevalone B (1318025-75-0)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2011.05.066