Propargyl-PEG5-beta-D-galactose

Base Information

Chemical Name:Propargyl-PEG5-beta-D-galactose
CAS No.:1397682-63-1
Molecular Formula:C₁₇H₃₀O₁₀
Molecular Weight:394.419
Hs Code.:

Synonyms:

Suppliers and Price of Propargyl-PEG5-beta-D-galactose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Propargyl-PEG5-beta-D-galactose 98%
250 MG
$ 880.00

Total 6 raw suppliers

Chemical Property of Propargyl-PEG5-beta-D-galactose

Chemical Property:

Boiling Point:578.6±50.0 °C(Predicted)
PKA:12.90±0.70(Predicted)
Density:1.29±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Propargyl-PEG5-beta-D-galactose 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Propargyl-PEG5-beta-D-glucose is a Click Chemistry-ready crosslinker containing a propargyl group and beta-D-glucose. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.

Technology Process of Propargyl-PEG5-beta-D-galactose

There total 5 articles about Propargyl-PEG5-beta-D-galactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1397682-61-9,1360446-31-6
3,6,9,12-tetraoxapentadec-14-ynyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside

: 1397682-63-1
{2-[2-(2-(2-propyn-1-yloxy)ethoxy)ethoxy]ethoxy}ethyl-β-D-galactopyranoside

Guidance literature:: With sodium methylate; In methanol; at 23 ℃; for 24h; pH=9 - 10;
DOI:10.1002/anie.201403186

Reference yield:

: 83-87-4,604-68-2,604-69-3,2152-77-4,4026-35-1,4163-59-1,4163-60-4,4163-61-5,4163-65-9,4257-94-7,4257-96-9,16299-15-3,19186-39-1,19189-55-0,25878-60-8,25941-03-1,32445-48-0,32445-49-1,32445-53-7,32445-54-8,34685-58-0,34685-59-1,43168-42-9,43168-44-1,43169-22-8,43169-25-1,66966-07-2,70749-17-6,80184-01-6,93221-01-3,93221-02-4,99630-88-3,109215-53-4,115792-70-6,115792-73-9,139894-92-1,139973-25-4,144071-49-8,147648-81-5
D-glucose pentaacetate

: 1397682-63-1
C₁₇H₃₀O₁₀

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / dichloromethane

2: sodium methylate; methanol / dichloromethane

With methanol; boron trifluoride diethyl etherate; sodium methylate; In dichloromethane;
DOI:10.1039/c6ra18613k