(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester

Base Information

Chemical Name:(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester
CAS No.:1246814-58-3
Molecular Formula:C₁₈H₁₈N₂O₄
Molecular Weight:326.352
Hs Code.:
DSSTox Substance ID:DTXSID10696498
Mol file:1246814-58-3.mol

Synonyms:1246814-58-3;(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester;Benzyl [1-(benzyloxy)-2-oxoazetidin-3-yl]carbamate;benzyl N-(2-oxo-1-phenylmethoxyazetidin-3-yl)carbamate;DTXSID10696498;CS-T-49002;FT-0662978

Suppliers and Price of (R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamicAcidBenzylEster
100mg
$ 120.00

American Custom Chemicals Corporation
(R,S)-[1-(BENZYLOXY)-2-OXO-3-AZETIDINYL]CARBAMIC ACID BENZYL ESTER 95.00%
5MG
$ 505.00

Total 2 raw suppliers

Chemical Property of (R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester

Chemical Property:

Solubility.:Ethyl Acetate
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:326.12665706
Heavy Atom Count:24
Complexity:431

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamicAcidBenzylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(=O)N1OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3
Uses Intermediate for synthesis of D,L-Alanosine.

Technology Process of (R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester

There total 11 articles about (R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 26048-94-2
(S)-{2-[(phenylmethyloxy)amino]-1-(hydroxymethyl)-2-oxoethyl}carbamic acid phenylmethyl ester

: 71404-99-4,1246814-58-3
(S)-[1-(phenylmethyloxy)-2-oxo-3-azetidinyl]carbamic acid phenylmethyl ester

Guidance literature:: With triethylamine; triphenylphosphine; In tetrachloromethane; acetonitrile; at 20 ℃; for 24h;
DOI:10.1002/ejoc.200400508

Reference yield: 86.0%

: 71605-41-9
O-benzyl-N-CBZ-β-chloro-L-alanine hydroxamate

: 71404-99-4,1246814-58-3
(S)-[1-(phenylmethyloxy)-2-oxo-3-azetidinyl]carbamic acid phenylmethyl ester

Guidance literature:: With sodium hydride; In dichloromethane; at 50 ℃; for 12h;
DOI:10.1021/ja00543a021

Reference yield:

: 622-33-3
N-benzyloxyamine

: 71404-99-4,1246814-58-3
(S)-[1-(phenylmethyloxy)-2-oxo-3-azetidinyl]carbamic acid phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / DCC / acetonitrile / 0 - 20 °C

2: 87 percent / PPh₃; Et₃N / acetonitrile; CCl₄ / 24 h / 20 °C

With triethylamine; dicyclohexyl-carbodiimide; triphenylphosphine; In tetrachloromethane; acetonitrile;
DOI:10.1002/ejoc.200400508