(R)-acetoxybutyronitrile

Base Information

• Chemical Name: (R)-acetoxybutyronitrile
• CAS No.: 134526-99-1
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127.143

Synonyms:

Chemical Property of (R)-acetoxybutyronitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of (R)-acetoxybutyronitrile

There total 2 articles about (R)-acetoxybutyronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetoxy-butyronitrile (54529-88-3) → (R)-3-hydroxybutanonitrile (125103-95-9) + (R)-acetoxybutyronitrile (134526-99-1) + (S)-acetoxybutyronitrile (134527-00-7)

Guidance literature:

With 1,4,8,11-tetrathiacyclotetradecane; Lipase PS; water; In acetone; at 35 ℃; the effect of different types of crown ethers on the enantioselectivity of lipase-catalyzed hydrolysis;

DOI:10.1021/jo951598+

Reference yield:

3-acetoxy-butyronitrile (54529-88-3) → 3-hydroxybutyronitrile (123689-95-2) + (R)-3-hydroxybutanonitrile (125103-95-9) + (R)-acetoxybutyronitrile (134526-99-1) + (S)-acetoxybutyronitrile (134527-00-7)

Guidance literature:

With (S)-methioninol; In acetone; for 14h; Product distribution; Mechanism; Ambient temperature; lipase PS, phosphate buffer, pH 7.2; other additives, various conc. of additives, 35 deg C;

DOI:10.1246/bcsj.64.624

upstream raw materials:

3-acetoxy-butyronitrile

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