2-Chloro-3-ethynylpyridine

Base Information

Chemical Name:2-Chloro-3-ethynylpyridine
CAS No.:1196156-69-0
Molecular Formula:C₇H₄ClN
Molecular Weight:137.568
Hs Code.:2933399990
European Community (EC) Number:893-963-9
DSSTox Substance ID:DTXSID10603824

Synonyms:2-chloro-3-ethynylpyridine;1196156-69-0;Pyridine, 2-chloro-3-ethynyl-;2-chloro-3-ethynyl-pyridine;SCHEMBL5700564;DTXSID10603824;AKOS026716019;AB69069;AT12435;CS-0210532;EN300-254465;F2147-2794

Suppliers and Price of 2-Chloro-3-ethynylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-3-ethynylpyridine
100mg
$ 130.00

TRC
2-Chloro-3-ethynylpyridine
10mg
$ 45.00

SynQuest Laboratories
2-Chloro-3-ethynylpyridine 95%
250 mg
$ 296.00

SynQuest Laboratories
2-Chloro-3-ethynylpyridine 95%
1 g
$ 888.00

Apolloscientific
2-Chloro-3-ethynylpyridine 95%
250mg
$ 269.00

Apolloscientific
2-Chloro-3-ethynylpyridine 95%
1g
$ 805.00

Anichem
2-Chloro-3-ethynyl-pyridine >95%
1g
$ 295.00

AK Scientific
2-Chloro-3-ethynylpyridine
500mg
$ 479.00

AK Scientific
2-Chloro-3-ethynylpyridine
250mg
$ 464.00

AK Scientific
2-Chloro-3-ethynylpyridine
100mg
$ 456.00

Total 3 raw suppliers

Chemical Property of 2-Chloro-3-ethynylpyridine

Chemical Property:

Boiling Point:224.9±25.0 °C(Predicted)
Density:1.23±0.1 g/cm3(Predicted)
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:137.0032268
Heavy Atom Count:9
Complexity:135

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-3-ethynylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=C(N=CC=C1)Cl

Technology Process of 2-Chloro-3-ethynylpyridine

There total 2 articles about 2-Chloro-3-ethynylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 470463-35-5
2-chloro-3-[2-(trimethylsilyl)ethynyl]pyridine

: 1196156-69-0
2-chloro-3-ethynylpyridine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1039/c4ob02549k

Reference yield:

: 52200-48-3
3-bromo-2-chloropyridine

: 1196156-69-0
2-chloro-3-ethynylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 20 °C

2: potassium hydroxide / methanol

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; potassium hydroxide; In methanol;
DOI:10.1039/c5ob02274f