3-(Bromomethyl)-4-methoxybenzonitrile

Base Information

Chemical Name:3-(Bromomethyl)-4-methoxybenzonitrile
CAS No.:101207-62-9
Molecular Formula:C₉H₈BrNO
Molecular Weight:226.073
Hs Code.:2926907090
European Community (EC) Number:854-067-3

Synonyms:3-(bromomethyl)-4-methoxybenzonitrile;101207-62-9;SCHEMBL7363416;FMGIAMOOHWQISI-UHFFFAOYSA-N;3-bromomethyl-4-methoxybenzonitrile;BEA20762;AKOS017552546;EN300-113389;G59409

Suppliers and Price of 3-(Bromomethyl)-4-methoxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Bromomethyl)-4-methoxybenzonitrile
100mg
$ 240.00

TRC
3-(Bromomethyl)-4-methoxybenzonitrile
50mg
$ 155.00

Alichem
5-Cyano-2-methoxybenzylbromide
250mg
$ 494.40

Alichem
5-Cyano-2-methoxybenzylbromide
1g
$ 1564.50

Alichem
5-Cyano-2-methoxybenzylbromide
500mg
$ 823.15

AK Scientific
3-(Bromomethyl)-4-methoxybenzonitrile
500mg
$ 749.00

Total 2 raw suppliers

Chemical Property of 3-(Bromomethyl)-4-methoxybenzonitrile

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:224.97893
Heavy Atom Count:12
Complexity:186

Purity/Quality:

95% ^*data from raw suppliers

3-(Bromomethyl)-4-methoxybenzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C#N)CBr

Technology Process of 3-(Bromomethyl)-4-methoxybenzonitrile

There total 2 articles about 3-(Bromomethyl)-4-methoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53078-71-0
4-methoxy-3-methylbenzonitrile

: 101207-62-9
3-bromomethyl-4-methoxybenzonitrile

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 2.5h;

Reference yield:

: 14804-31-0
2-methyl-4-bromoanisole

: 101207-62-9
3-bromomethyl-4-methoxybenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / N,N-dimethyl-formamide / 16 h / 80 °C

2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 16 h / 95 °C / Inert atmosphere

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; N,N-dimethyl-formamide;

Reference yield:

: 101207-62-9
3-bromomethyl-4-methoxybenzonitrile

: 3-((2-amino-4-hydroxy-6-methylpyrimidin-5-yl)methyl)-4-methoxybenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere

1.2: 15 h / 0 - 70 °C / Inert atmosphere

2.1: methanol / 16 h / 70 °C

With sodium hydride; In tetrahydrofuran; methanol; mineral oil;