(3R)-3-(4-fluorophenyl)pyrrolidine

Base Information

Chemical Name:(3R)-3-(4-fluorophenyl)pyrrolidine
CAS No.:1048703-18-9
Molecular Formula:C₁₀H₁₂FN
Molecular Weight:165.21
Hs Code.:
DSSTox Substance ID:DTXSID901298405

Synonyms:(3R)-3-(4-fluorophenyl)pyrrolidine;1048703-18-9;(R)-3-(4-Fluoro-phenyl)-pyrrolidine;(R)-3-(4-FLUOROPHENYL)PYRROLIDINE;SCHEMBL1828844;DTXSID901298405;(R)-3-(4-fluorophenyl)-pyrrolidine;AT37651;CS-0440199

Suppliers and Price of (3R)-3-(4-fluorophenyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(3R)-3-(4-Fluorophenyl)pyrrolidine 96%
250 mg
$ 543.00

SynQuest Laboratories
(3R)-3-(4-Fluorophenyl)pyrrolidine 96%
1 g
$ 1467.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
5g
$ 4880.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
1g
$ 1380.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
500mg
$ 740.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
250mg
$ 420.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
100mg
$ 260.00

J&W Pharmlab
(R)-3-(4-Fluoro-phenyl)-pyrrolidine 96%
50mg
$ 180.00

Total 4 raw suppliers

Chemical Property of (3R)-3-(4-fluorophenyl)pyrrolidine

Chemical Property:

Boiling Point:241.8±33.0 °C(Predicted)
Density:1.078±0.06 g/cm3(Predicted)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.095377549
Heavy Atom Count:12
Complexity:141

Purity/Quality:

99%, ^*data from raw suppliers

(3R)-3-(4-Fluorophenyl)pyrrolidine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CNCC1C2=CC=C(C=C2)F
Isomeric SMILES:C1CNC[C@H]1C2=CC=C(C=C2)F
Uses (R)-3-(4-Fluorophenyl)pyrrolidine is a quinoline that is used as CRTH2 receptor modulators.

Technology Process of (3R)-3-(4-fluorophenyl)pyrrolidine

There total 5 articles about (3R)-3-(4-fluorophenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1201986-72-2
(R)-tert-butyl 3-(4-fluorophenyl)pyrrolidine-1-carboxylate

: 1048703-18-9
(R)-3-(4-fluoro-phenyl)-pyrrolidine

Guidance literature:: (R)-tert-butyl 3-(4-fluorophenyl)pyrrolidine-1-carboxylate; With hydrogenchloride; water; In 1,4-dioxane; at 0 - 5 ℃; for 1h;

With ammonia; In methanol; pH=7;

Reference yield:

: 144620-11-1,1048703-18-9
3-(4-fluorophenyl)pyrrolidine

: 1048703-18-9
(R)-3-(4-fluoro-phenyl)-pyrrolidine

Guidance literature:: With (+)-di-O,O-p-tolyl tartaric acid; In ethanol; at 0 - 60 ℃; Resolution of racemate;

Reference yield:

: 220474-60-2
1-benzyl-3-(4'-fluorophenyl)pyrrolidine

: 144620-11-1,1048703-18-9
3-(4-fluorophenyl)pyrrolidine

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; Ambient temperature;
DOI:10.1016/S0960-894X(99)00201-2