C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

Base Information

Chemical Name:C₂₅H₂₈⁽²⁾H₄F₃N₃O₄
CAS No.:1426173-86-5
Molecular Formula:C₂₅H₃₂F₃N₃O₄
Molecular Weight:499.51
Hs Code.:

C<sub>25</sub>H<sub>28</sub><sup>(2)</sup>H<sub>4</sub>F<sub>3</sub>N<sub>3</sub>O<sub>4</sub>

Synonyms:

Suppliers and Price of C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Silodosin-d4
1mg
$ 160.00

Medical Isotopes, Inc.
Silodosin-d4
1 mg
$ 790.00

Cayman Chemical
Silodosin-d4
1mg
$ 599.00

Total 5 raw suppliers

Chemical Property of C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

Chemical Property:

Purity/Quality:

95% by HPLC; 95% atom D ^*data from raw suppliers

Silodosin-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Silodosin-d4 is an isotopic labelled form of Silodosin (S465000). Silodosin is an α1a-Adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.

Technology Process of C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

There total 11 articles about C₂₅H₂₈⁽²⁾H₄F₃N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: C₃₂H₃₀⁽²⁾H₄F₃N₃O₄

: 1426173-86-5
C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

Guidance literature:: C₃₂H₃₀⁽²⁾H₄F₃N₃O₄; With sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃;

With dihydrogen peroxide; In dimethyl sulfoxide; at 0 - 20 ℃; for 24h; Inert atmosphere;
DOI:10.1515/hc-2017-0092

Reference yield:

: 239463-72-0,1201180-97-3
5-[(2R)-2-aminopropyl]-2,3-dihydro-1-[3-(benzoyloxy)propyl]-1H-indole-7-carbonitrile

: 1426173-86-5
C₂₅H₂₈⁽²⁾H₄F₃N₃O₄

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetonitrile / 12 h / 80 °C

2.1: sodium hydroxide / tetrahydrofuran; methanol / 20 °C

2.2: 24 h / 0 - 20 °C / Inert atmosphere

With tetra-(n-butyl)ammonium iodide; potassium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1515/hc-2017-0092

Reference yield:

: 1051374-60-7
(R)-1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoro-1-d2-ethoxy)phenoxy)ethyl-d4-amino)propyl)indoline-7-carbonitrile

: 1051374-51-6,1426173-86-5
(R)-1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-d2-trifluoroethoxy)phenoxy)-d4-ethylamino)propyl)indoline-7-carboxamide

Guidance literature:: (R)-1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoro-1-d2-ethoxy)phenoxy)ethyl-d4-amino)propyl)indoline-7-carbonitrile; With water; dihydrogen peroxide; In dimethyl sulfoxide; for 0.166667h;

With sodium hydroxide; water; In dimethyl sulfoxide; for 1h;