14-[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]-10,12-tetradecadiynoic acid

Base Information

• Chemical Name: 14-[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]-10,12-tetradecadiynoic acid
• CAS No.: 140427-97-0
• Molecular Formula: C21H22F12O3
• Molecular Weight: 550.37800
• Mol file: 140427-97-0.mol

Synonyms:

Chemical Property of 14-[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]-10,12-tetradecadiynoic acid

Chemical Property:

• PSA: 46.53000
• LogP: 6.65680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 14-[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]-10,12-tetradecadiynoic acid

There total 2 articles about 14-[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]-10,12-tetradecadiynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol (335-99-9) → 14-(1,1,7-trihydroperfluoroheptyloxy)tetradecane-10,12-diynoic acid (140427-97-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / benzyltrimethylammonium chloride, 40percent aq. KOH / benzene / 8 h / 20 - 60 °C

2: 1.) CuCl, NH₂OH*HCl, MeNH₂ / 1.) methanol, 2.) methanol, 4 h

With potassium hydroxide; hydroxylamine hydrochloride; benzyltrimethylammonium chloride; methylamine; copper(l) chloride; In benzene;

Reference yield:

11-bromo-10-undecynoic acid (13030-63-2) + 3-(1,1,7-trihydroperfluoroheptyloxy)-1-propyne (140427-89-0) → 10,12-docosadiynedioic acid (28393-02-4) + 14-(1,1,7-trihydroperfluoroheptyloxy)tetradecane-10,12-diynoic acid (140427-97-0)

Guidance literature:

With hydroxylamine hydrochloride; methylamine; copper(l) chloride; Multistep reaction. Yields of byproduct given; 1.) methanol, 2.) methanol, 4 h;

upstream raw materials:

11-bromo-10-undecynoic acid

3-(1,1,7-trihydroperfluoroheptyloxy)-1-propyne

2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol