335-99-9

Basic information

• Product Name: 1H,1H,7H-DODECAFLUORO-1-HEPTANOL
• Synonyms: 7H 6:1 FTOH;1H,1H,7H-PERFLUORO-1-HEPTANOL;1H,1H,7H-DODECAFLUORO-1-HEPTANOL;1H,1H,7H-DODECAFLUOROFLUOROHEPTANOL-1;1H,1H,7H-DODECAFLUOROHEPTAN-1-OL;1H,1H,7H-DODECAFLUOROHEPTANOL;1H,1H,7H-PERFLUOROHEPTAN-1-OL;1,1,7-TRIHYDROPERFLUOROHEPTANOL
• CAS NO: 335-99-9
• Molecular Formula: C₇H₄F₁₂O
• Molecular Weight: 332.09
• EINECS: 206-406-6
• Product Categories: Small molecule;Fluorous Chemistry;Fluorous Compounds;Synthetic Organic Chemistry
• Mol File: 335-99-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: -20°C
• Boiling Point: 169-170 °C
• Flash Point: 169-170°C
• Appearance: colorless liquid.
• Density: 1.76
• Vapor Pressure: 4.23mmHg at 25°C
• Refractive Index: 1.316-1.318
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.89±0.10(Predicted)
• BRN: 1800110
• CAS DataBase Reference: 1H,1H,7H-DODECAFLUORO-1-HEPTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,1H,7H-DODECAFLUORO-1-HEPTANOL(335-99-9)
• EPA Substance Registry System: 1H,1H,7H-DODECAFLUORO-1-HEPTANOL(335-99-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• RTECS: MJ4500000
• TSCA: Yes
• Hazardous Substances Data: 335-99-9(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless liquid

InChI:InChI=1S/C7H4F12O/c8-2(9)4(12,13)6(16,17)7(18,19)5(14,15)3(10,11)1-20/h2,20H,1H2

Upstream product

• 302-17-0 chloral hydrate 
• 111257-10-4 C₁₅H₉F₂₄O₂P 
• 80032-16-2 C₂₅H₁₉F₃₆NO₃S 
• 67-56-1 methanol 
• 116-14-3 polytetrafluoroethylene 
• 85878-31-5 C₁₃H₈F₁₃NO₃STe 
• 85892-57-5 C₂₀H₁₁F₂₄NO₄STe 
• 2648-47-7 2,2,3,3,4,4,5,5-octafluorovaleraldehyde 
• 65611-18-9 tris(1,1,7-trihydrododecafluoroheptyl)phosphite 
• 56002-71-2 trimethyl-(1H,1H,7H-dodecafluoroheptyloxy)silane 
• 78491-64-2 C₂₈H₁₂F₄₈O₄S 
• 97916-17-1 C₁₄H₆Cl₂F₂₄O₂Te 

Downstream Products

• 381-08-8 Bis--bis-<1H,1H,7H-dodecafluor-heptyloxy>-silan 
• 65064-82-6 7-(1,1,2,3,3,3-hexafluoropropoxy)-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluoroheptane 
• 992-81-4 <1,1,7-Trihydro-perfluor-heptyl>-orthobenzoat 
• 2261-99-6 1H,1H,7H-dodecafluoroheptyl methacrylate 
• 424-16-8 1,1,7-trihydroperfluoroheptyl toluenesulfonate 
• 2993-85-3 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl acrylate 
• 799-34-8 (2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyloxymethyl)oxirane 
• 78971-81-0 2,2,3,3,4,4,5,5,6,6,7,7-decafluoroheptyl vinyl ether 
• 26185-31-9 <2,6-Dinitro-4-trifluormethyl-phenyl>-<1H,1H,7H-dodecafluor-heptyl>-ether 
• 10368-42-0 1,1,7-Trihydro-perfluorheptyl-(2,4-dinitro-phenyl-)ether 
• 128816-79-5 (2,2,2-trifluoroethyl)(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)(α-trifluoromethylbenzyl) phosphate 
• 1546-95-8 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoic acid 
• 17351-92-7 2,2,3,3,4,4,5,5,6,7,7-dodecafluoroheptyl trifluoromethanesulfonate 
• 23588-89-8 triethylamine hydrofluoride 

Relevant articles and documents

Polyfluoroalkoxy phosphonic and phosphinic acid derivatives: II. Reversible esterase inhibitors

Polyfluoroalkyl esters of phosphoric, alkylphosphonic and 1-hydroxypolyfluoroalkylphosphonic acids exhibited significant antiesterase activity against various esterases of animal and microbial origin. Moreover, with some compounds reversible inhibition of enzymes was observed due to the specific influence of hydrophobic fragments of the target products.

Process for hydroxyalkylation of fluorinated alcohols

Mono O-hydroxyalkylated derivatives of 1,1-dihydroperfluorinated or 1H,1-alkylperfluorinated alcohols are prepared by reacting the alcohols with alkylene carbonates at a temperature of at least 60° C. in the presence of a one- or two-part catalyst. The catalyst is a nitrogenous base, optionally in combination with a tetraalkylammonium halide. The O-hydroxyalkylated derivatives are useful non-ionic surfactants and emulsifiable compounds for fire extinguishing systems.

COMPOUNDS WITH A TELLURIUM-NITROGEN BOND. Y. POLYFLUOROALKOXYHALOGENO- AND POLYFLUOROALKOXYAMINOTELLURANES

The reaction of tetrakis(polyfluoroalkoxy)telluranes with tellurium tetrahalides leads to the production of mixed polyfluoroalkoxyhalogenotelluranes.The reaction of the polyfluoroalkoxyhalogenotelluranes with silylated secondary amines and hexamethyldisilylbenzenesulfonamide leads to the formation of derivatives of hydroxyaminotelluranes and N,N-bis(phenylsulfonyl)tellurium diimide.