3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopentaphenanthren

• Chemical Name: 3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopentaphenanthren
• Molecular Formula: C₃₅H₅₄N₂O₄S
• Molecular Weight: 598.891
• Mol file: 3296-28-4.mol

Synonyms:

Chemical Property of 3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopenta

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopenta

There total 1 articles about 3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopentaphenanthren which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopentaphenanthren (3296-28-4)

Guidance literature:

Cyclomicrophyllin-A, Toluol-4-sulfonylchlorid, Py.;

DOI:10.1039/jr9650004512

Reference yield:

3-Dimethylamino-17-<1-dimethylamino-aethyl>-4-p-toluolsulfonyloxymethyl-16-hydroxy-4,13,14-trimethyl-1,2,3,4,5,8,11,12,13,14,15,16-dodecahydro-17H,19H-cyclopropa<9,10>cyclopentaphenanthren (3296-28-4) → 4,4-Dimethyl-dihydro-cyclomicrophyllin (808-94-6)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) PhCH₂SH, DMF, (ii) Raney-Ni, aq. EtOH

2: H₂, AcOH / PtO₂

With hydrogen; acetic acid; platinum(IV) oxide;

DOI:10.1039/j39660001412

Downstream raw materials:

4,4-Dimethyl-dihydro-cyclomicrophyllin