furan-3-yl(thiophen-2-yl)methanol

Base Information

• Chemical Name: furan-3-yl(thiophen-2-yl)methanol
• CAS No.: 1185651-39-1
• Molecular Formula: C₉H₈O₂S
• Molecular Weight: 180.227
• Mol file: 1185651-39-1.mol

Synonyms:

Chemical Property of furan-3-yl(thiophen-2-yl)methanol

Chemical Property:

Purity/Quality:

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Technology Process of furan-3-yl(thiophen-2-yl)methanol

There total 1 articles about furan-3-yl(thiophen-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-bromofurane (22037-28-1) + thiophene-2-carbaldehyde (98-03-3) → furan-3-yl(thiophen-2-yl)methanol (1185651-39-1,136260-84-9)

Guidance literature:

3-bromofurane; With n-butyllithium; In hexane; tert-butyl methyl ether; at -78 ℃; Inert atmosphere;

With ethylzinc chloride; In hexane; tert-butyl methyl ether; toluene; at -78 ℃; for 0.5h; Inert atmosphere;

thiophene-2-carbaldehyde; optical yield given as %ee; enantioselective reaction; Further stages;

DOI:10.1021/ja9046747

upstream raw materials:

3-bromofurane

thiophene-2-carbaldehyde