Thio-PEG2-t-butyl ester

Base Information

• Chemical Name: Thio-PEG2-t-butyl ester
• CAS No.: 1398044-50-2
• Molecular Formula: C₁₁H₂₂O₄S
• Molecular Weight: 250.359
• Mol file: 1398044-50-2.mol

Synonyms:

Chemical Property of Thio-PEG2-t-butyl ester

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Thiol-PEG2-t-butylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Thio-PEG2-t-butyl ester

There total 3 articles about Thio-PEG2-t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C13H24O5S (1820641-93-7) → C11H22O4S (1398044-50-2)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 2h;

DOI:10.1002/anie.201804437

Reference yield:

2-methyl-2-propanyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate (133803-81-3,892154-71-1) → C11H22O4S (1398044-50-2)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 14 h / 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 4 h / 60 °C / Inert atmosphere

3: sodium methylate / methanol / 2 h / 20 °C

With sodium methylate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/anie.201804437

Reference yield:

9-(p-toluenesulfonyloxy)-3,6-diocanonanoic acid tert-butyl ester (850090-13-0) → C11H22O4S (1398044-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 4 h / 60 °C / Inert atmosphere

2: sodium methylate / methanol / 2 h / 20 °C

With sodium methylate; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/anie.201804437

upstream raw materials:

2-methyl-2-propanyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate

9-(p-toluenesulfonyloxy)-3,6-diocanonanoic acid tert-butyl ester

C₁₃H₂₄O₅S