C₅₃H₅₄N₂O₂

Base Information

Chemical Name:C₅₃H₅₄N₂O₂
CAS No.:1908437-58-0
Molecular Formula:C₅₃H₅₄N₂O₂
Molecular Weight:751.024
Hs Code.:

C<sub>53</sub>H<sub>54</sub>N<sub>2</sub>O<sub>2</sub>

Synonyms:

Suppliers and Price of C₅₃H₅₄N₂O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₅₃H₅₄N₂O₂

Chemical Property:

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Safty Information:

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Technology Process of C₅₃H₅₄N₂O₂

There total 3 articles about C₅₃H₅₄N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 18880-00-7
1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

: 139021-82-2,157904-66-0
2,2′-methylene bis[(4R,5S)-4,5-diphenyl-2-oxazoline]

: 2361262-51-1,1908437-58-0
(4R,4'R,5S,5'S)-2,2'-(1,3-bis(4-(tert-butyl)phenyl)propane-2,2-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole)

Guidance literature:: 2,2′-methylene bis[(4R,5S)-4,5-diphenyl-2-oxazoline]; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 1h;

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene; In tetrahydrofuran; mineral oil; at 20 ℃; for 6h;
DOI:10.1021/acs.orglett.6b00570

Reference yield: 62.0%

: 18880-00-7
1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

: 157904-66-0
2,2'-methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline]

: 2361262-51-1,1908437-58-0
C₅₃H₅₄N₂O₂

Guidance literature:: 2,2'-methylenebis[(4R,5S)-4,5-diphenyl-2-oxazoline]; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h;

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 8h;
DOI:10.1021/acs.orglett.9b01552

Reference yield:

: 23190-16-1
(1R,2S)-2-Amino-1,2-diphenylethanol

: 2361262-51-1,1908437-58-0
C₅₃H₅₄N₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 24 h / 20 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C

2.2: 8 h / 0 - 20 °C

With sodium hydride; In tetrahydrofuran; dichloromethane; mineral oil;
DOI:10.1021/acs.orglett.9b01552