1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone

Base Information

Chemical Name:1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone
CAS No.:478040-86-7
Molecular Formula:C₁₇H₁₆N₂O
Molecular Weight:264.327
Hs Code.:
DSSTox Substance ID:DTXSID901320646
ChEMBL ID:CHEMBL1493285
Mol file:478040-86-7.mol

Synonyms:478040-86-7;1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone;1-[1-(2-phenylethyl)-1H-1,3-benzodiazol-2-yl]ethan-1-one;1-[1-(2-phenylethyl)benzimidazol-2-yl]ethanone;MLS000706903;CHEMBL1493285;DTXSID901320646;HMS2701C24;MFCD02186509;AKOS005089409;SMR000335720;3R-0705

Suppliers and Price of 1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(1-PHENETHYL-1H-1,3-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
1-(1-PHENETHYL-1H-1,3-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
1-(1-PHENETHYL-1H-1,3-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
1MG
$ 647.61

Total 1 raw suppliers

Chemical Property of 1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:264.126263138
Heavy Atom Count:20
Complexity:338

Purity/Quality:: 1-(1-PHENETHYL-1H-1,3-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=NC2=CC=CC=C2N1CCC3=CC=CC=C3

Technology Process of 1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone

There total 2 articles about 1-(1-phenethyl-1H-1,3-benzimidazol-2-yl)-1-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 201230-82-2
carbon monoxide

: 80-43-3
bis(1-methyl-1-phenylethyl)peroxide

: 22492-13-3
1-phenethyl-1H-benzo[d]imidazole

: 478040-86-7
1-(1-phenethyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Guidance literature:: With acetic acid; In 1,2-dichloro-ethane; chlorobenzene; at 140 ℃; for 20h; under 37503.8 Torr; Autoclave;
DOI:10.1002/ejoc.201901728

Reference yield:

: 51-17-2,79351-71-6
benzoimidazole

: 103-63-9
1-phenyl-2-bromoethane

: 478040-86-7
1-(1-phenethyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / 0 - 20 °C / Sealed tube

1.2: 12 h / 80 °C / Sealed tube

2.1: acetic acid / chlorobenzene; 1,2-dichloro-ethane / 20 h / 140 °C / 37503.8 Torr / Autoclave

With sodium hydride; acetic acid; In tetrahydrofuran; 1,2-dichloro-ethane; chlorobenzene; mineral oil;
DOI:10.1002/ejoc.201901728