mPEG bromoisobutyrate

Base Information

• Chemical Name: mPEG bromoisobutyrate
• CAS No.: 245070-97-7
• Molecular Formula: C₇H₁₃BrO₃
• Molecular Weight: 225.082
• Mol file: 245070-97-7.mol

Synonyms:

Chemical Property of mPEG bromoisobutyrate

Chemical Property:

• Refractive Index: n20/D1.465
• Flash Point: >110°C
• Density: 1.214 g/mL at 25 °C
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Poly(ethylene glycol) methyl ether 2-bromoisobutyrate average M ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Poly(ethylene glycol)-containing ATRP initiator for generating a block copolymer with a PEG block on one end. The PEG block is terminated with an unreactive methoxy group. PEG functionalized with bromoisobutyryl group to initiate atom transfer radical polymerization (ATRP). This macroinitiator can be used to increase biocompatibility; hydrophilicity; or generate block copolymers.

Technology Process of mPEG bromoisobutyrate

There total 1 articles about mPEG bromoisobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-methoxy-ethanol (109-86-4,95507-80-5) + 2-bromoisobutyric acid bromide (20769-85-1) → 2-methoxyethyl 2-bromoisobutyrate (1267624-34-9,245070-97-7)

Guidance literature:

With triethylamine; In chloroform; Cooling with ice;

DOI:10.1002/anie.201607581

upstream raw materials:

2-methoxy-ethanol

2-bromoisobutyric acid bromide

Refernces

• 1、 Li, Yinwen,Zheng, Xiuwen,Zhu, Huayu,Wu, Kun,Lu, Mangeng. "Synthesis and self-assembly of well-defined binary graft copolymer and its use in superhydrophobic cotton fabrics preparation". . p. 46132 - 46145. Retrieved 2015/06/08.
• 2、 Sun, Jianping,Hu, Jiwen,Liu, Guojun,Xiao, Dingshu,He, Guping,Lu, Rufeng. "Efficient synthesis of well-defined amphiphilic cylindrical brushes polymer with high grafting density: Interfacial "click" chemistry approach". scheme or table. p. 1282 - 1288. Retrieved 2012/02/15.