3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid

Base Information

• Chemical Name: 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid
• CAS No.: 60736-75-6
• Molecular Formula: C₁₈H₁₉ClO₄
• Molecular Weight: 334.799
• Mol file: 60736-75-6.mol

Synonyms:

Chemical Property of 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid

There total 7 articles about 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.8%

→ 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid (60736-75-6)

Guidance literature:

Reference yield:

isopropoxybenzene (2741-16-4) → 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid (60736-75-6)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl

2: (i) NaOEt, (ii) /BRN= 743157/, (iii) aq. NaOH

With hydrogenchloride;

DOI:10.1135/cccc19771723

Reference yield:

2-Chloroanisole (766-51-8) → 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid (60736-75-6)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl, As₂O₃

3: (i) aq. HBr, (ii) /BRN= 1098229/, HCl

4: (i) NaOEt, (ii) /BRN= 743157/, (iii) aq. NaOH

With hydrogenchloride; arsenic(III) trioxide;

DOI:10.1135/cccc19771723

upstream raw materials:

methyl 3-chloro-4-hydroxyphenylacetate

1-(Chloromethyl)-4-(1-methylethoxy)benzene

3-chloro-4-methoxybenzyl chloride

isopropoxybenzene