1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea

Base Information

Chemical Name:1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea
CAS No.:231957-54-3
Molecular Formula:C₁₉H₁₇FN₄O₃
Molecular Weight:368.367
Hs Code.:
UNII:824VSI942Y
DSSTox Substance ID:DTXSID70177773
Wikidata:Q27269302
ChEMBL ID:CHEMBL391735

Synonyms:MIV 150;MIV-150;MIV150;PC 817;PC-817;PC817 cpd

Suppliers and Price of 1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
MIV-1R
10mg
$ 910.00

Cayman Chemical
MIV-150 ≥98%
10mg
$ 890.00

Cayman Chemical
MIV-150 ≥98%
5mg
$ 623.00

Cayman Chemical
MIV-150 ≥98%
1mg
$ 160.00

Cayman Chemical
MIV-150 ≥98%
500μg
$ 89.00

AK Scientific
Miv-150
10mg
$ 1301.00

Total 2 raw suppliers

Chemical Property of 1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:368.12846858
Heavy Atom Count:27
Complexity:621

Purity/Quality:

≥98% ^*data from raw suppliers

MIV-1R ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)C1=C(C(=C(C=C1)F)C2CC2NC(=O)NC3=NC=C(C=C3)C#N)O
Isomeric SMILES:CCC(=O)C1=C(C(=C(C=C1)F)[C@@H]2C[C@@H]2NC(=O)NC3=NC=C(C=C3)C#N)O
Uses MIV-1R is an allosteric inhibitor of reverse transcriptase that is active in HIV-1 and HIV-2 . Shown to inactivate viruses that are resistant to other antiviral drugs.

Technology Process of 1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea

There total 17 articles about 1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%