C₁₂H₁₀FNO₂

Base Information

• Chemical Name: C₁₂H₁₀FNO₂
• CAS No.: 1565845-75-1
• Molecular Formula: C₁₂H₁₀FNO₂
• Molecular Weight: 219.215
• Hs Code.: 2934999090
• Mol file: 1565845-75-1.mol

Synonyms:

Chemical Property of C₁₂H₁₀FNO₂

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

1-[2-(4-Fluorophenyl)-4-methyl-1,3-oxazol-5-yl]ethan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₀FNO₂

There total 1 articles about C₁₂H₁₀FNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

p-fluorobenzamide (824-75-9) + acetylacetone (123-54-6,81235-32-7) → C12H10FNO2 (1565845-75-1)

Guidance literature:

With dipotassium peroxodisulfate; acetic acid; copper(I) bromide; In 1,1,2,2-tetrachloroethane; at 140 ℃; for 36h; Inert atmosphere;

DOI:10.1039/c4ra14394a

Reference yield:

C12H10FNO2 (1565845-75-1) → 2-(4-fluorophenyl)-4-methyl-5-(2-phenylthiazol-4-yl)oxazole

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / dichloromethane / 0.17 h / 0 °C

1.2: 12 h / 0 - 20 °C

2.1: ethanol / Reflux

With toluene-4-sulfonic acid; In ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2017.03.065

Reference yield:

C12H10FNO2 (1565845-75-1) → 5-(2-(4-bromophenyl)thiazol-4-yl)-2-(4-fluorophenyl)-4-methyloxazole

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / dichloromethane / 0.17 h / 0 °C

1.2: 12 h / 0 - 20 °C

2.1: ethanol / Reflux

With toluene-4-sulfonic acid; In ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2017.03.065

upstream raw materials:

p-fluorobenzamide

acetylacetone