leuprolide

Base Information

• Chemical Name: leuprolide
• CAS No.: 1872435-00-1
• Molecular Formula: C₅₉H₈₄N₁₆O₁₂
• Molecular Weight: 1209.42

Synonyms:

Chemical Property of leuprolide

Chemical Property:

• Density: 1.44±0.1 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

LEUPROLIDE IMPURITY F 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of leuprolide

There total 4 articles about leuprolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C104H138N16O17S → Leuprolide (1872435-00-1)

Guidance literature:

With triethylsilane; trifluoroacetic acid; In methanol; water; at 20 ℃; for 2h;

DOI:10.1039/c7nj04720g

Reference yield:

C78H98N16O12 → Leuprolide (1872435-00-1)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; In water; at 20 ℃; for 2h;

DOI:10.1021/jo302127d

Reference yield:

ethylamine (75-04-7,85404-22-4) → leuprolide (1872435-00-1)

Guidance literature:

With ethylenediaminetetraacetic acid; methyl-phenyl-thioether; methoxybenzene; trifluoroacetic acid; Yield given. Multistep reaction; 1.) CHCl₃, 2.) 4 h;

DOI:10.1016/S0040-4020(97)00029-X

upstream raw materials:

ethylamine

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