acetyl-thio-hexaethyleneglycol

Base Information

• Chemical Name: acetyl-thio-hexaethyleneglycol
• CAS No.: 165729-83-9
• Molecular Formula: C₁₄H₂₈O₇S
• Molecular Weight: 340.438
• Mol file: 165729-83-9.mol

Synonyms:

Chemical Property of acetyl-thio-hexaethyleneglycol

Chemical Property:

Purity/Quality:

Ac-S-dPEG?(12)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetyl-thio-hexaethyleneglycol

There total 19 articles about acetyl-thio-hexaethyleneglycol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

8-tosyloxy-3,6-dioxaoctanol (77544-68-4) + potassium thioacetate (10387-40-3) → S-(2-(2-(2-hydroxyethoxy)ethoxy)ethyl) ethanethioate (153870-20-3,165729-83-9)

Guidance literature:

In acetone; for 2.5h; Heating;

DOI:10.1016/S0040-4020(01)80247-7

Reference yield: 95.0%

1-O-trityl-11-thioacetyl-3,6,9-trioxa-undecanol (223611-41-4) → S-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl)thioacetate (223611-42-5,165729-83-9)

Guidance literature:

With tetrafluoroboric acid; water; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/(SICI)1521-3773(19990401)38:7<974::AID-ANIE974>3.0.CO;2-K

Reference yield: 93.0%

5-tosyloxy-3-oxapentanol (118591-58-5) + potassium thioacetate (10387-40-3) → thioacetic acid S-[2-(2-hydroxy-ethoxy)-ethyl] ester (374925-82-3,165729-83-9)

Guidance literature:

With 18-crown-6 ether; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1002/ejoc.201402902

upstream raw materials:

8-tosyloxy-3,6-dioxaoctanol

potassium thioacetate

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

2-[2-(ethenyloxy)ethoxy]ethan-1-ol

Downstream raw materials:

2-(2-(2-(2-(pyridin-2-yldisulfanyl)ethoxy)ethoxy)ethoxy)ethan-1-ol

1-amino-17-mercapto-3, 6,9,12,15,-pentaoxa-heptadecanol