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Methyltetrazine-PEG4-NHS Ester

Base Information
  • Chemical Name:Methyltetrazine-PEG4-NHS Ester
  • CAS No.:1802907-92-1
  • Molecular Formula:C24H31N5O9
  • Molecular Weight:533.538
  • Hs Code.:
Methyltetrazine-PEG4-NHS Ester

Synonyms:

Suppliers and Price of Methyltetrazine-PEG4-NHS Ester
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Iris Biotech GmbH
  • MeTz-PEG(4)-NHS
  • 500 mg
  • $ 2794.50
  • Iris Biotech GmbH
  • MeTz-PEG(4)-NHS
  • 100 mg
  • $ 864.00
  • Iris Biotech GmbH
  • MeTz-PEG(4)-NHS
  • 10 mg
  • $ 270.00
  • Iris Biotech GmbH
  • MeTz-PEG(4)-NHS
  • 25 mg
  • $ 391.50
  • Chem-Impex
  • Methyltetrazine-PEG4-NHSester,95%(HPLC) 95%(HPLC)
  • 100MG
  • $ 515.20
  • Chem-Impex
  • Methyltetrazine-PEG4-NHSester,≥95%(HPLC) ≥95%(HPLC)
  • 25MG
  • $ 291.20
  • BroadPharm
  • Methyltetrazine-PEG5-NHSester 95%
  • 10 MG
  • $ 139.00
  • BroadPharm
  • Methyltetrazine-PEG5-NHSester 95%
  • 100 MG
  • $ 575.00
  • Ambeed
  • Methyltetrazine-PEG5-nhsester 95%
  • 1g
  • $ 3983.00
  • Ambeed
  • Methyltetrazine-PEG5-nhsester 95%
  • 250mg
  • $ 1589.00
Total 8 raw suppliers
Chemical Property of Methyltetrazine-PEG4-NHS Ester
Chemical Property:
  • Boiling Point:697.9±65.0 °C(Predicted) 
  • PKA:1.67±0.10(Predicted) 
  • Density:1.35±0.1 g/cm3(Predicted) 
  • Storage Temp.:-20°C 
Purity/Quality:

97% *data from raw suppliers

MeTz-PEG(4)-NHS *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description Methyltetrazine-PEG5-NHS Ester is a click chemistry crosslinker containing a methyltetrazine group. THe hydrophilic PEG spacer improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. Methyltetrazine enable click chemistry with TCO (trans-cycloctene).
  • Uses Methyltetrazine-PEG4-NHS ester is a crosslinker with enhanced stability and water solubility. This crosslinker has an NHS ester that can be reacted with a primary amine and a methyltetrazine that is reactive with trans-cyclooctenes. Methyltetrazine-PEG4-NHS ester is one of the most stable tetrazines commercially available. In addition to stabilization provided by the electron donating methyl group, the electron donating alkoxy substituent on the aromatic ring further improves the stability of methyltetrazine-PEG4-NHS ester. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.
Technology Process of Methyltetrazine-PEG4-NHS Ester

There total 1 articles about Methyltetrazine-PEG4-NHS Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 35 ℃;
DOI:10.1021/jacs.0c05331
upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

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