hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

Base Information

Chemical Name:hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
CAS No.:367272-52-4
Molecular Formula:C₂₁H₂₄N₂O₄*ClH
Molecular Weight:404.894
Hs Code.:

Synonyms:

Suppliers and Price of hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-lysineMonohydrochloride
2.5g
$ 1320.00

Labseeker
D-lysine,N6-[(9H-fluren-9-ylmethoxy)carbonyl]hexanoicacid-monohydrochloridesalt 98
15g
$ 833.00

Total 0 raw suppliers

Chemical Property of hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

Chemical Property:

Purity/Quality:: N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-lysineMonohydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-lysine Monohydrochloride is a protected form of D-Lysine (L468930). D-Lysine is the unnatural isomer of L-Lysine (L468895) that has the ability to reduce non-enzymatic glycation in vitro. D-Lysine also exists as polypeptide chains of poly-D-lysine, a nonspecific adhesion-promoting molecule that has the potential to be a polymeric drug carrier.

Technology Process of hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

There total 2 articles about hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 84624-27-1
Boc-Lys(Fmoc)-OH

: 253138-02-2,367272-52-4
(S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

Reference yield:

: 84624-27-1
Boc-Lys(Fmoc)-OH

: 367272-52-4
hydrochloride of (S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

Guidance literature:: With hydrogenchloride;

Reference yield:

: 253138-02-2,367272-52-4
(S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid hydrochloride

: 76-83-5
trityl chloride

: 1596360-18-7
9H-fluoren-9-ylmethyl N-[(5S)-5-cyano-5-(tritylamino)pentyl]carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 6 h / 20 °C / Cooling

2: triethylamine; ammonium chloride; trifluoroacetic anhydride / tetrahydrofuran / 0.08 h / Cooling

With ammonium chloride; triethylamine; trifluoroacetic anhydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2014.02.002