6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Base Information

Chemical Name:6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile
CAS No.:932028-72-3
Molecular Formula:C₁₉H₁₅N₃O₂
Molecular Weight:317.347
Hs Code.:
DSSTox Substance ID:DTXSID30582960
Nikkaji Number:J2.432.526A
Mol file:932028-72-3.mol

Synonyms:DTXSID30582960;6-ACETYL-3-OXO-2,5-DIPHENYL-2,3,4,5-TETRAHYDROPYRIDAZINE-4-CARBONITRILE;932028-72-3

Suppliers and Price of 6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:317.116426730
Heavy Atom Count:24
Complexity:577

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=NN(C(=O)C(C1C2=CC=CC=C2)C#N)C3=CC=CC=C3

Technology Process of 6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

There total 3 articles about 6-Acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 932028-68-7
6-acetyl-3-amino-2,5-diphenyl-2,5-dihydro-pyridazine-4-carbonitrile

: 932028-72-3
6-acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Guidance literature:: With hydrogenchloride; water; acetic acid; for 0.25h; Reflux;
DOI:10.3987/COM-08-11373

Reference yield:

: 2700-22-3
Benzylidenemalononitrile

: 5391-74-2
1-(phenylhydrazono)-propan-2-one

: 932028-72-3
6-acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / ethanol

2: hydrogenchloride; water; acetic acid / 0.25 h / Reflux

With piperidine; hydrogenchloride; water; acetic acid; In ethanol;
DOI:10.3987/COM-08-11373

Reference yield:

: 100-52-7
benzaldehyde

: 5391-74-2
1-(phenylhydrazono)-propan-2-one

: 932028-72-3
6-acetyl-3-oxo-2,5-diphenyl-2,3,4,5-tetrahydropyridazine-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: chitozan / ethanol / Reflux

2: hydrogenchloride; water; acetic acid / 0.25 h / Reflux

With hydrogenchloride; water; acetic acid; In ethanol;
DOI:10.3987/COM-08-11373