3-Cyclopentene-1-acetaldehyde

Base Information

• Chemical Name: 3-Cyclopentene-1-acetaldehyde
• CAS No.: 14055-37-9
• Molecular Formula: C7H10O
• Molecular Weight: 110.156
• DSSTox Substance ID: DTXSID90472979
• Nikkaji Number: J917.106A
• Mol file: 14055-37-9.mol

Synonyms:3-Cyclopentene-1-acetaldehyde;14055-37-9;2-(CYCLOPENT-3-EN-1-YL)ACETALDEHYDE;2-cyclopent-3-en-1-ylacetaldehyde;SCHEMBL3355258;DTXSID90472979

Chemical Property of 3-Cyclopentene-1-acetaldehyde

Chemical Property:

• PSA: 17.07000
• LogP: 1.54160
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 110.073164938
• Heavy Atom Count: 8
• Complexity: 97

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C=CCC1CC=O

Technology Process of 3-Cyclopentene-1-acetaldehyde

There total 5 articles about 3-Cyclopentene-1-acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(hydroxymethyl)cyclopentene (25125-21-7) → 2-(cyclopent-3-en-1-yl)acetaldehyde (14055-37-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂

2: dimethylsulfoxide / 70 °C

3: 68 percent / DIBAL-H / CH₂Cl₂ / -78 °C

With diisobutylaluminium hydride; triethylamine; In dichloromethane; dimethyl sulfoxide;

DOI:10.1055/s-2006-941603

Reference yield:

4-(hydroxymethyl)cyclopentene (25125-21-7) → 2-(cyclopent-3-en-1-yl)acetaldehyde (14055-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 17.83 h / 0 °C

2: diisobutylaluminium hydride / tetrahydrofuran / 0.5 h / -70 °C

With diisobutylaluminium hydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;

Reference yield:

exo-5-norbornen-2-ol (2890-98-4,13080-90-5,16620-80-7,69769-90-0,71030-14-3,71030-15-4,87392-59-4,106928-44-3,694-97-3) → 2-(cyclopent-3-en-1-yl)acetaldehyde (14055-37-9) + 2-(cyclopent-2-enyl)acetaldehyde (19656-91-8,695-08-9)

Guidance literature:

In pentane; Yield given. Yields of byproduct given; Irradiation;

DOI:10.1021/ja00542a048

upstream raw materials:

exo-5-norbornen-2-ol

endo-5-norbornen-2-ol

p-Toluolsulfonsaeure-<6endo-brom-2endo-norbornyl>ester

4-(hydroxymethyl)cyclopentene

Downstream raw materials:

(R)-2-oxo-1-phenyl-2-(piperidin-1-yl)ethyl 4-(cyclopent-3-enyl)-3-oxobutanoate