VK-II-36

Base Information

• Chemical Name: VK-II-36
• CAS No.: 955371-66-1
• Molecular Formula: C₂₆H₂₆N₂O₅
• Molecular Weight: 446.503
• Mol file: 955371-66-1.mol

Synonyms:

Chemical Property of VK-II-36

Chemical Property:

• Boiling Point: 698.6±55.0 °C(Predicted)
• PKA: 16.54±0.30(Predicted)
• Density: 1.271±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

VK-II-36 >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of VK-II-36

There total 6 articles about VK-II-36 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

→ 6-[(9H-carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-3-morpholinone (955371-66-1)

Guidance literature:

Reference yield:

C26H27ClN2O5 → 6-[(9H-carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-3-morpholinone (955371-66-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1021/jm401090a

Reference yield:

carvedilol (72956-09-3) + chloroacetyl chloride (79-04-9) → 6-[(9H-carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-3-morpholinone (955371-66-1)

Guidance literature:

carvedilol; chloroacetyl chloride; With triethylamine; In chloroform; at 20 ℃;

With sodium hydride; In tetrahydrofuran; at 20 ℃;

upstream raw materials:

4-(2,3-epoxypropoxy)carbazole

2-(2-methoxy-phenoxy)-ethylamine

carvedilol

chloroacetyl chloride