4-FLUORO-3'-METHOXYBENZHYDROL

Base Information

Chemical Name:4-FLUORO-3'-METHOXYBENZHYDROL
CAS No.:844856-35-5
Molecular Formula:C₁₄H₁₃FO₂
Molecular Weight:232.254
Hs Code.:
Mol file:844856-35-5.mol

Synonyms:

Suppliers and Price of 4-FLUORO-3'-METHOXYBENZHYDROL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-FLUORO-3'-METHOXYBENZHYDROL
1g
$ 809.00

Rieke Metals
4-FLUORO-3'-METHOXYBENZHYDROL
5g
$ 1943.00

Crysdot
(4-Fluorophenyl)(3-methoxyphenyl)methanol 97%
5g
$ 1429.00

Total 2 raw suppliers

Chemical Property of 4-FLUORO-3'-METHOXYBENZHYDROL

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-FLUORO-3'-METHOXYBENZHYDROL ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of 4-FLUORO-3'-METHOXYBENZHYDROL

There total 11 articles about 4-FLUORO-3'-METHOXYBENZHYDROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1594124-08-9
(S)-2-((3-methoxyphenyl)(m-tolyl)methyl)-5,5-dimethyl-1,3,2-dioxaborinane

: 1594124-25-0,844683-32-5
(S)-(3-methoxyphenyl)(m-tolyl)methanol

: 844856-35-5
(R)-(4-fluorophenyl)(3-methoxyphenyl)methanol

Guidance literature:: With dihydrogen peroxide; sodium hydroxide; In diethyl ether; Overall yield = 72 %; Overall yield = 12 mg; Further stages; Inert atmosphere;
DOI:10.1021/ja412159g

Reference yield:

: 458569-45-4
3-methoxybenzyl N,N-diisopropylcarbamate

: 1594124-25-0,844683-32-5
(S)-(3-methoxyphenyl)(m-tolyl)methanol

: 844856-35-5
(R)-(4-fluorophenyl)(3-methoxyphenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: (4S)-2,2'-(1-Ethylpropylidene)bis<4-(1-methylethyl)-4,5-dihydrooxazole> / diethyl ether / 0.5 h / -78 °C / Inert atmosphere

1.2: 3.33 h / -78 °C / Inert atmosphere

2.1: sodium hydroxide; dihydrogen peroxide / diethyl ether / Inert atmosphere

With dihydrogen peroxide; (4S)-2,2'-(1-Ethylpropylidene)bis<4-(1-methylethyl)-4,5-dihydrooxazole>; sodium hydroxide; In diethyl ether;
DOI:10.1021/ja412159g

Reference yield:

: 6971-51-3
3-methoxybenzyl alcohol

: 1594124-25-0,844683-32-5
(S)-(3-methoxyphenyl)(m-tolyl)methanol

: 844856-35-5
(R)-(4-fluorophenyl)(3-methoxyphenyl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 24 h / Inert atmosphere; Reflux

2.1: (4S)-2,2'-(1-Ethylpropylidene)bis<4-(1-methylethyl)-4,5-dihydrooxazole> / diethyl ether / 0.5 h / -78 °C / Inert atmosphere

2.2: 3.33 h / -78 °C / Inert atmosphere

3.1: sodium hydroxide; dihydrogen peroxide / diethyl ether / Inert atmosphere

With dihydrogen peroxide; triethylamine; (4S)-2,2'-(1-Ethylpropylidene)bis<4-(1-methylethyl)-4,5-dihydrooxazole>; sodium hydroxide; In diethyl ether; dichloromethane;
DOI:10.1021/ja412159g