(αR,2R)-α-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(hydroxyiMino)acetyl]aMino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid

Base Information

Chemical Name:(αR,2R)-α-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(hydroxyiMino)acetyl]aMino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid
CAS No.:937819-42-6
Molecular Formula:C₁₄H₁₅N₅O₆S₂
Molecular Weight:413.435
Hs Code.:
Mol file:937819-42-6.mol

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Chemical Property of (αR,2R)-α-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(hydroxyiMino)acetyl]aMino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid

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Uses (αR,2R)-α-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(hydroxyimino)acetyl]amino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid, is the the impurity of Cefdinir (C242670), a Cephalosporin antibiotic structurally similar to Cefixime. It can be used to treat infections caused by several Gram-negative and Gram-positive bacteria.

Technology Process of (αR,2R)-α-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(hydroxyiMino)acetyl]aMino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid

There total 2 articles about (αR,2R)-α-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(hydroxyiMino)acetyl]aMino]-4-carboxy-5-ethenyl-3,6-dihydro-2H-1,3-thiazine-2-acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₁₅N₅O₆S₂*C₆H₁₅N

: 71091-93-5
3-methyl cefdinir

: 937819-42-6
C₁₄H₁₅N₅O₆S₂

: 91832-40-5,178601-88-2
cefdinir

: 178601-88-2
7β-[(E)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetamido]-3-vinylcephem-4-carboxylic acid

Guidance literature:: C₁₆H₁₅N₅O₆S₂*C₆H₁₅N; With ammonium chloride; potassium carbonate; In tetrahydrofuran; at 20 - 25 ℃; for 0.166667h; pH=5;

With sulfuric acid; at 20 - 40 ℃; pH=2.5 - 2.6; Further stages. Title compound not separated from byproducts.;