Adomeglivant

Base Information

Chemical Name:Adomeglivant
CAS No.:1488363-78-5
Molecular Formula:C₃₂H₃₆F₃NO₄
Molecular Weight:555.637
Hs Code.:
Mol file:1488363-78-5.mol

Synonyms:

Suppliers and Price of Adomeglivant

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Adomeglivant >98%
250 mg
$ 600.00

ChemScene
Adomeglivant 99.84%
100mg
$ 780.00

ChemScene
Adomeglivant 99.84%
25mg
$ 288.00

ChemScene
Adomeglivant 99.84%
50mg
$ 528.00

ChemScene
Adomeglivant 99.84%
10mg
$ 180.00

ChemScene
Adomeglivant 99.84%
5mg
$ 120.00

Cayman Chemical
Adomeglivant
5mg
$ 94.00

Cayman Chemical
Adomeglivant
1mg
$ 25.00

Cayman Chemical
Adomeglivant
10mg
$ 175.00

Cayman Chemical
Adomeglivant
25mg
$ 375.00

Total 7 raw suppliers

Chemical Property of Adomeglivant

Chemical Property:

Boiling Point:656.7±55.0 °C(Predicted)
PKA:4.28±0.10(Predicted)
Density:1.173±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Adomeglivant >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Adomeglivant

There total 18 articles about Adomeglivant which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: ethyl (S)-3-{4-[1-(4'-tert-butyl-2,6-dimethylbiphenyl-4-yloxy)-4,4,4-trifluorobutyl]benzamido}propanoate

: 1488363-78-5
(S)-3-{4-[1-(4'-tert-butyl-2,6-dimethylbiphenyl-4-yloxy)-4,4,4-trifluorobutyl]benzamido}propanoic acid

Guidance literature:: With water; sodium hydroxide; at 20 ℃; for 18h;
DOI:10.1021/acs.orglett.5b00782

Reference yield:

: C₁₀H₁₀BrF₃O

: 1488363-78-5
(S)-3-{4-[1-(4'-tert-butyl-2,6-dimethylbiphenyl-4-yloxy)-4,4,4-trifluorobutyl]benzamido}propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 h / 0 - 20 °C / Inert atmosphere

2: palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium carbonate / toluene / Heating

3: sodium hydroxide; water / 18 h / 20 °C

With di-isopropyl azodicarboxylate; water; palladium diacetate; sodium carbonate; triphenylphosphine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide; In tetrahydrofuran; toluene;
DOI:10.1021/acs.orglett.5b00782

Reference yield:

: C₂₈H₃₀BrF₃O

: 1488363-78-5
(S)-3-{4-[1-(4'-tert-butyl-2,6-dimethylbiphenyl-4-yloxy)-4,4,4-trifluorobutyl]benzamido}propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium carbonate / toluene / Heating

2: sodium hydroxide; water / 18 h / 20 °C

With water; palladium diacetate; sodium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide; In toluene;
DOI:10.1021/acs.orglett.5b00782