3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester

Base Information

Chemical Name:3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester
CAS No.:318510-90-6
Molecular Formula:C₁₅H₂₁NO₄
Molecular Weight:279.336
Hs Code.:
Mol file:318510-90-6.mol

Synonyms:

Suppliers and Price of 3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Labseeker
3-(4-tert-Butoxycarbonylamino-phenyl)-propionicacidmethylester 95
1g
$ 1467.00

Total 1 raw suppliers

Chemical Property of 3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester

Chemical Property:

Purity/Quality:: 3-(4-tert-Butoxycarbonylamino-phenyl)-propionicacidmethylester 95 ^*data from reagent suppliers

Safty Information:

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Technology Process of 3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester

There total 5 articles about 3-(4-tert-Butoxycarbonylamino-phenyl)-propionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: (E)-methyl 3-(4-((tert-butoxycarbonyl)amino)phenyl)acrylate

: 318510-90-6
methyl 3-(4-((tert-butoxycarbonyl)amino)phenyl)propanoate

Guidance literature:: With palladium 10% on activated carbon; ammonium formate; In methanol; for 4h; Reflux; Inert atmosphere;
DOI:10.1021/acs.jmedchem.7b00678

Reference yield:

: 224635-57-8
⁽³⁾-[4-(tert-Butoxycarbonylamino)phenyl]-propenoic acid methyl ester

: 318510-90-6
methyl 3-(4-((tert-butoxycarbonyl)amino)phenyl)propanoate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 3h;
DOI:10.1039/c3md00214d

Reference yield:

: 159217-89-7
N-Boc-4-iodoaniline

: 318510-90-6
methyl 3-(4-((tert-butoxycarbonyl)amino)phenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; bis(triphenylphosphine)palladium(II) dichloride; lithium chloride / N,N-dimethyl-formamide / 3 h / 130 °C / Inert atmosphere; Microwave irradiation; Sealed tube

2: hydrogen; palladium 10% on activated carbon / methanol / 3 h / 20 °C

With bis(triphenylphosphine)palladium(II) dichloride; palladium 10% on activated carbon; hydrogen; triethylamine; lithium chloride; In methanol; N,N-dimethyl-formamide; 1: |Heck Reaction;
DOI:10.1039/c3md00214d