2-nitro-7-hydroxybenzofuran

Base Information

• Chemical Name: 2-nitro-7-hydroxybenzofuran
• CAS No.: 40739-73-9
• Molecular Formula: C₈H₅NO₄
• Molecular Weight: 179.132
• Mol file: 40739-73-9.mol

Synonyms:7-Hydroxy-2-nitrobenzofuran

Chemical Property of 2-nitro-7-hydroxybenzofuran

Chemical Property:

• Vapor Pressure: 1.65E-05mmHg at 25°C
• Boiling Point: 354.3°C at 760 mmHg
• Flash Point: 168.1°C
• PSA: 79.19000
• Density: 1.536g/cm³
• LogP: 2.56980
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Nitrobenzofuran-7-ol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-7-hydroxybenzofuran

There total 1 articles about 2-nitro-7-hydroxybenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

bromonitromethane (563-70-2) + 2,3-dihydroxybenzaldehyde (24677-78-9) → 2-nitro-7-hydroxybenzofuran (40739-73-9)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 25 ℃; for 0.5h;

Reference yield: 88.0%

2-nitro-7-hydroxybenzofuran (40739-73-9) + benzoyl chloride (98-88-4) → 2-nitro-7-benzoyloxybenzofuran (96089-25-7)

Guidance literature:

In pyridine; for 12h; Ambient temperature;

upstream raw materials:

bromonitromethane

2,3-dihydroxybenzaldehyde

Downstream raw materials:

2-nitro-7-benzoyloxybenzofuran

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