2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester

Base Information

• Chemical Name: 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester
• CAS No.: 85531-16-4
• Molecular Formula: C₂₃H₁₆O₈
• Molecular Weight: 420.375
• Mol file: 85531-16-4.mol

Synonyms:

Chemical Property of 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester

Chemical Property:

• Melting Point: 148-150°C
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

99% ^*data from raw suppliers

2-[[2-(Acetyloxy)benzoyl]oxy]benzoicAcid2-CarboxyphenylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: An analog of Aspirin (acetyl salicylic acid, A187780), which acts as an analgesic, antipyretic, anti-inflammatory, and antithrombotic.

Technology Process of 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester

There total 2 articles about 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aspirin (50-78-2,98201-60-6) → 2-hydroxy-benzoic acid, 2-carboxyphenyl ester (552-94-3) + acetylsalicylsalicylic acid (530-75-6) + 2-{2-[2-(2-acetoxy-benzoyloxy)-benzoyloxy]-benzoyloxy}-benzoic acid (85539-30-6) + tri-salicylic acid (85531-17-5) + C23H16O8 (85531-16-4) + salicylic acid (69-72-7,25496-36-0,8052-31-1)

Guidance literature:

With magnesium carbonate; at 85 ℃; for 2h; Product distribution; also in benzene or toluene with or without magnesium carbonate;

DOI:10.1002/jps.2600720331

Reference yield:

tri-salicylic acid (85531-17-5) → C23H16O8 (85531-16-4)

Guidance literature:

DOI:10.1002/jps.2600720331

Reference yield:

C23H16O8 (85531-16-4) + methyl iodide (74-88-4) → C24H18O8

Guidance literature:

DOI:10.1002/jps.2600720331

upstream raw materials:

aspirin

tri-salicylic acid

Refernces