2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride

Base Information

• Chemical Name: 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride
• CAS No.: 1111841-67-8
• Molecular Formula: C₁₂H₁₆ClN₃O*ClH
• Molecular Weight: 290.192
• Mol file: 1111841-67-8.mol

Synonyms:

Chemical Property of 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride

There total 2 articles about 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile (213009-04-2) + isopropylamine (75-31-0) → 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride (1111841-67-8)

Guidance literature:

2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile; isopropylamine; In ethanol; for 13h; Reflux;

With hydrogenchloride;

DOI:10.1038/s41401-018-0200-x

Reference yield:

→ 2-(4-amino-3-chloro-5-cyanophenyl)-2-isopropylaminoethanol hydrochloride (1111841-67-8)

Guidance literature:

upstream raw materials:

2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile

isopropylamine