213009-04-2

Basic information

• Product Name: 2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile
• CAS NO: 213009-04-2
• Molecular Weight: 275.532
• Mol File: 213009-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile(213009-04-2)
• EPA Substance Registry System: 2-Amino-5-(2-bromo-1-hydroxy-ethyl)-3-chloro-benzonitrile(213009-04-2)

Safety Data

• Hazardous Substances Data: 213009-04-2(Hazardous Substances Data)

Upstream product

• 88167-51-5 2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile 
• 67-56-1 methanol 

Downstream Products

• 213009-00-8 Acetic acid 1-(4-amino-3-chloro-5-cyano-phenyl)-2-bromo-ethyl ester 

Relevant articles and documents

Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol has been achieved by ethanol enantioselective lipase-catalysed alcoholysis, hydrolysis and acylation. Although a good enantioselectivity was observed in the three reactions, the best results were obtained by hydrolysis. This α- bromohydrin is an intermediate in the synthesis of a new adrenergic agent.