Benzenamine, 2-(diphenylphosphino)-N-methyl-

Base Information

• Chemical Name: Benzenamine, 2-(diphenylphosphino)-N-methyl-
• CAS No.: 140669-65-4
• Molecular Formula: C19H18NP
• Molecular Weight: 291.332
• DSSTox Substance ID: DTXSID90476477
• Nikkaji Number: J1.024.299A
• Wikidata: Q82307887
• Mol file: 140669-65-4.mol

Synonyms:140669-65-4;2-(Diphenylphosphino)-N-methylaniline;Benzenamine, 2-(diphenylphosphino)-N-methyl-;SCHEMBL18729658;DTXSID90476477

Chemical Property of Benzenamine, 2-(diphenylphosphino)-N-methyl-

Chemical Property:

• PSA: 25.62000
• LogP: 3.55950
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 291.117686576
• Heavy Atom Count: 21
• Complexity: 276

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=CC=CC=C1P(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Benzenamine, 2-(diphenylphosphino)-N-methyl-

There total 7 articles about Benzenamine, 2-(diphenylphosphino)-N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(2-Methylamino-phenyl)-triphenyl-phosphonium; chloride (140669-68-7) → 2-(diphenylphosphino)-N-methylaniline (140669-65-4)

Guidance literature:

With sodium naphthalenide; In tetrahydrofuran; for 1h;

Reference yield: 70.0%

phenyl diphenylphosphinite (13360-92-4) + N-methylaniline (100-61-8) → 2-(diphenylphosphino)-N-methylaniline (140669-65-4)

Guidance literature:

N-methylaniline; With n-butyllithium; In hexane; at 20 ℃; Inert atmosphere; Schlenk technique; Glovebox;

With carbon dioxide; In diethyl ether; hexane; at -78 ℃; Inert atmosphere; Schlenk technique; Glovebox;

phenyl diphenylphosphinite; Further stages;

DOI:10.1021/om400899g

Reference yield: 64.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + N-methylaniline (100-61-8) → 2-(diphenylphosphino)-N-methylaniline (140669-65-4)

Guidance literature:

N-methylaniline; With n-butyllithium; In tetrahydrofuran; at -70 ℃; Inert atmosphere;

With carbon dioxide; In tetrahydrofuran; at 0 - 10 ℃; Inert atmosphere;

chloro-diphenylphosphine; Further stages;

DOI:10.1021/ja803011d

upstream raw materials:

chloro-diphenylphosphine

N-methylaniline

(2-Methylamino-phenyl)-triphenyl-phosphonium; chloride

(2-chloroanilino)methylsuccinimide

Downstream raw materials:

[NiCl(P(CH₃)3)(N-methyl-2-(diphenylphosphanyl)aniline)] hexafluorophosphate

trans-(P,P)-[Ir(CO)(PPh3)(2-diphenylphosphanyl-N-methylanilido-κN,κP)]

[W(CO)4(2-Ph₂PC₆H₄N(H)Me)]

[2-(diphenylphosphanyl)-N-methylanilido-N,P](methyl)(trimethylphosphane)nickel(II)