1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one

Base Information

Chemical Name:1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one
CAS No.:116941-59-4
Molecular Formula:C₁₂H₁₃NO
Molecular Weight:187.241
Hs Code.:
DSSTox Substance ID:DTXSID901232237

Synonyms:1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one;DTXSID901232237;116941-59-4

Suppliers and Price of 1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:187.099714038
Heavy Atom Count:14
Complexity:264

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C(=CC(=O)N1C2=CC=CC=C2)C

Technology Process of 1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one

There total 2 articles about 1,5-Dihydro-4,5-dimethyl-1-phenyl-2H-pyrrol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: {P(C₆H₁₁)3}NiCH(CH₃)CH₂C(O)N(C₆H₅)

: 75-36-5
acetyl chloride

: 116941-59-4
4,5-dimethyl-1-phenyl-1,5-dihydro-pyrrol-2-one

Guidance literature:: In not given; cyclisation first with acetylchloride, then reaction with H3O(+);
DOI:10.1016/0022-328X(88)80488-1

Reference yield:

: 187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4
propene

: 103-71-9
phenyl isocyanate

: 75-36-5
acetyl chloride

: 116941-59-4
4,5-dimethyl-1-phenyl-1,5-dihydro-pyrrol-2-one

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sulfuric acid; tricyclohexylphosphine; Yield given. Multistep reaction; 1.) THF, -78 deg C -> r.t., 20 h; 2.) THF, 20 deg C, 24 h;
DOI:10.1016/0022-328X(88)80488-1