6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester

Base Information

• Chemical Name: 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester
• CAS No.: 40514-96-3
• Molecular Formula: C₂₃H₂₄N₂O₃S₂
• Molecular Weight: 440.587
• Mol file: 40514-96-3.mol

Synonyms:

Chemical Property of 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester

There total 4 articles about 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (3956-31-8,49626-54-2,64519-71-7) → 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester (40514-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol

2: (i) NaH, DMF, (ii) /BRN= 1446059/

In methanol;

DOI:10.1021/jo00956a027

Reference yield:

benzaldehyde (100-52-7) → 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester (40514-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol

2: (i) NaH, DMF, (ii) /BRN= 1446059/

In methanol;

DOI:10.1021/jo00956a027

Reference yield:

6β-benzylideneamino-penicillanic acid benzyl ester (41926-39-0) + methanethiosulfonic acid S-methyl ester (2949-92-0,31761-75-8) → 6β-benzylideneamino-6α-methylsulfanyl-penicillanic acid benzyl ester (40514-96-3)

Guidance literature:

Multistep reaction; (i) NaH, DMF, (ii) /BRN= 1446059/;

DOI:10.1021/jo00956a027

upstream raw materials:

6β-benzylideneamino-penicillanic acid benzyl ester

methanethiosulfonic acid S-methyl ester

benzyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

benzaldehyde

Downstream raw materials:

6β-amino-6α-methylsulfanyl-penicillanic acid benzyl ester; toluene-4-sulfonate