C₂₃H₂₇N₃O₄

Base Information

• Chemical Name: C₂₃H₂₇N₃O₄
• CAS No.: 1360473-49-9
• Molecular Formula: C₂₃H₂₇N₃O₄
• Molecular Weight: 409.485
• Mol file: 1360473-49-9.mol

Synonyms:

Chemical Property of C₂₃H₂₇N₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₇N₃O₄

There total 5 articles about C₂₃H₂₇N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-cylohexanedione (504-02-9) → C23H27N3O4 (1360473-50-2) + C23H27N3O4 (1360473-49-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium cyanoborohydride; L-proline / ethanol / 85 °C / Molecular sieve; Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: n-butyllithium / N,N,N,N,N,N-hexamethylphosphoric triamide; toluene / -78 - 20 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -78 °C / Inert atmosphere

4.1: [D₃]acetonitrile / 25 °C / Inert atmosphere

With n-butyllithium; diisobutylaluminium hydride; sodium cyanoborohydride; L-proline; In N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; [D₃]acetonitrile; toluene;

DOI:10.1021/jo300188y

Reference yield:

C16H18O4 (1383842-71-4) → C23H27N3O4 (1360473-50-2) + C23H27N3O4 (1360473-49-9)

Guidance literature:

Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -78 °C / Inert atmosphere

2: [D₃]acetonitrile / 25 °C / Inert atmosphere

With diisobutylaluminium hydride; In dichloromethane; [D₃]acetonitrile; toluene;

DOI:10.1021/jo300188y

Reference yield:

3,4,5-trimethoxy-2-iodobenzaldehyde (73252-53-6) → C23H27N3O4 (1360473-50-2) + C23H27N3O4 (1360473-49-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium cyanoborohydride; L-proline / ethanol / 85 °C / Molecular sieve; Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: n-butyllithium / N,N,N,N,N,N-hexamethylphosphoric triamide; toluene / -78 - 20 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -78 °C / Inert atmosphere

4.1: [D₃]acetonitrile / 25 °C / Inert atmosphere

With n-butyllithium; diisobutylaluminium hydride; sodium cyanoborohydride; L-proline; In N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; [D₃]acetonitrile; toluene;

DOI:10.1021/jo300188y

upstream raw materials:

C₁₆H₁₈O₄

C₁₆H₂₀O₄

benzyl azide

2-(2-iodo-3,4,5-trimethoxybenzyl)-3-oxocyclohex-1-en-1-yl trifluoromethanesulfonate