PRN-1371

Base Information

Chemical Name:PRN-1371
CAS No.:1802929-43-6
Molecular Formula:C₂₆H₃₀Cl₂N₆O₄
Molecular Weight:561.468
Hs Code.:
Mol file:1802929-43-6.mol

Synonyms:

Suppliers and Price of PRN-1371

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
PRN1371 >98%
250 mg
$ 1900.00

DC Chemicals
PRN1371 >98%
1 g
$ 3800.00

ChemScene
PRN1371 99.72%
100mg
$ 2100.00

ChemScene
PRN1371 99.72%
50mg
$ 1500.00

ChemScene
PRN1371 99.72%
10mg
$ 500.00

ChemScene
PRN1371 99.72%
5mg
$ 300.00

ChemScene
PRN1371 99.72%
1mg
$ 90.00

Total 10 raw suppliers

Chemical Property of PRN-1371

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

PRN1371 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of PRN-1371

There total 21 articles about PRN-1371 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4670-10-4
(3,5-dimethoxyphenyl)acetic acid

: 1802929-43-6
6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-[4-(prop-2-enoyl)piperazin-1-yl]propyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: sulfuric acid / Reflux; Large scale

2.1: potassium carbonate; caesium carbonate / dimethyl sulfoxide / 15 h / 50 °C / Large scale

3.1: potassium carbonate / dimethyl sulfoxide / Large scale

3.2: 5 h / 0 - 20 °C / Large scale

4.1: triethylamine; N-chloro-succinimide; acetic acid / 2 h / 20 - 30 °C / Large scale

5.1: ethyl acetate; tetrahydrofuran / 30 °C / Large scale

6.1: N,N-dimethyl-formamide; water / 1 h / 0 - 20 °C

With N-chloro-succinimide; sulfuric acid; potassium carbonate; caesium carbonate; acetic acid; triethylamine; In tetrahydrofuran; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: tert-butyl-4-(3-(6-(3,5-dimethoxyphenyl)-2-(methylthio)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)propyl)piperazine-1-carboxylate 4-methylbenzenesulfonate

: 1802929-43-6
6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-[4-(prop-2-enoyl)piperazin-1-yl]propyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; N-chloro-succinimide; acetic acid / 2 h / 20 - 30 °C / Large scale

2: ethyl acetate; tetrahydrofuran / 30 °C / Large scale

3: N,N-dimethyl-formamide; water / 1 h / 0 - 20 °C

With N-chloro-succinimide; acetic acid; triethylamine; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 6512-32-9
methyl 2-(3,5-dimethoxyphenyl)acetate

: 1802929-43-6
6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-[4-(prop-2-enoyl)piperazin-1-yl]propyl]-7H,8H-pyrido[2,3-d]pyrimidin-7-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate; caesium carbonate / dimethyl sulfoxide / 15 h / 50 °C / Large scale

2.1: potassium carbonate / dimethyl sulfoxide / Large scale

2.2: 5 h / 0 - 20 °C / Large scale

3.1: triethylamine; N-chloro-succinimide; acetic acid / 2 h / 20 - 30 °C / Large scale

4.1: ethyl acetate; tetrahydrofuran / 30 °C / Large scale

5.1: N,N-dimethyl-formamide; water / 1 h / 0 - 20 °C

With N-chloro-succinimide; potassium carbonate; caesium carbonate; acetic acid; triethylamine; In tetrahydrofuran; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;